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4.2.1.157: (R)-2-hydroxyisocaproyl-CoA dehydratase

This is an abbreviated version!
For detailed information about (R)-2-hydroxyisocaproyl-CoA dehydratase, go to the full flat file.

Word Map on EC 4.2.1.157

Reaction

(R)-2-hydroxy-4-methylpentanoyl-CoA
=
4-methylpent-2-enoyl-CoA
+
H2O

Synonyms

2-hydroxyisocaproyl-CoA dehydratase, HadBC, HadBC dehydratase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.157 (R)-2-hydroxyisocaproyl-CoA dehydratase

Cloned

Cloned on EC 4.2.1.157 - (R)-2-hydroxyisocaproyl-CoA dehydratase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
genes hadB and hadC are encoded in the hadABC locus
I6WYY7; P9WFJ9
overexpression in Escherichia coli
the hadBC and hadI genes from Clostridium difficile are functionally expressed in Escherichia coli. They encode the 2-hydroxyisocaproyl-CoA dehydratase HadBC and its activator HadI