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4.2.1.155: (methylthio)acryloyl-CoA hydratase

This is an abbreviated version!
For detailed information about (methylthio)acryloyl-CoA hydratase, go to the full flat file.

Reaction

3-(methylsulfanyl)acryloyl-CoA
+ 2 H2O =
acetaldehyde
+
methanethiol
+
CoA
+
CO2

Synonyms

DmdD, MTA-CoA hydratase, SPO3805

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.155 (methylthio)acryloyl-CoA hydratase

Crystallization

Crystallization on EC 4.2.1.155 - (methylthio)acryloyl-CoA hydratase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystals of the wild-type enzyme and the E121A mutant enzyme are grown at 20°C by the hanging-drop vapor diffusion method. Crystal structure of the free enzyme at 1.5 A resolution, structures of the E121A mutant in complex with methylthioacryloyl-CoA and 3-methylmercaptopropionate-CoA at 1.8 A resolution