4.2.1.154: tetracenomycin F2 cyclase

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For detailed information about tetracenomycin F2 cyclase, go to the full flat file.

Reaction

Synonyms

Tcm F2 cyclase, tcmI, TcmI cyclase

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.154 tetracenomycin F2 cyclase

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Results	in table
10	AA Sequence
1	Cloned(Commentary)
1	Crystallization (Commentary)
8	kcat/KM [mM/s]
9	KM Value [mM]
3	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
4	Organism
7	Pathway
1	pH Range
7	Protein Variants
2	Purification (Commentary)
1	Reaction
4	Reference
2	Specific Activity [micromol/min/mg]
4	Substrates and Products (Substrate)
5	Subunits
8	Synonyms
1	Systematic Name
8	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 4.2.1.154 - tetracenomycin F2 cyclase

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SYSTEMATIC NAME

IUBMB Comments

tetracenomycin F2 hydro-lyase (tetracenomycin-F1-forming)

The enzyme is involved in biosynthesis of the anthracycline antibiotic tetracenomycin C by the bacterium Streptomyces glaucescens.