4.2.1.144: 3-amino-5-hydroxybenzoate synthase
This is an abbreviated version!
For detailed information about 3-amino-5-hydroxybenzoate synthase, go to the full flat file.
Word Map on EC 4.2.1.144
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4.2.1.144
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ansamycins
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polyketide
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rifamycins
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amycolatopsis
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starter
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actinomycete
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mediterranei
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geldanamycin
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synthases
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endophytic
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cosmid
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pyridoxal
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antibiotic-producing
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naphthalenic
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mitomycin
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maytansine
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maytansinoids
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gene-positive
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hygroscopicus
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erythromycin
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carbamoyl
-
ansamitocin
- 4.2.1.144
-
ansamycins
- polyketide
- rifamycins
- amycolatopsis
-
starter
-
actinomycete
- mediterranei
- geldanamycin
- synthases
-
endophytic
-
cosmid
- pyridoxal
-
antibiotic-producing
-
naphthalenic
- mitomycin
-
maytansine
-
maytansinoids
-
gene-positive
- hygroscopicus
- erythromycin
-
carbamoyl
-
ansamitocin
Reaction
Synonyms
3-amino-5-hydroxybenzoic acid synthase, AHBA synthase, rifK
ECTree
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Cofactor
Cofactor on EC 4.2.1.144 - 3-amino-5-hydroxybenzoate synthase
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pyridoxal 5'-phosphate
enzyme is a dimer containing one molecule of pyridoxal phosphate per subunit. The enzyme-bound pyridoxal phosphate forms a Schiffs base with the amino group of 5-deoxy-5-amino-3-dehydroshikimic acid and catalyzes both an alpha,beta-dehydration and a stereospecific 1,4-enolization of the substrate