4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase
This is an abbreviated version!
For detailed information about 2-dehydro-3-deoxy-D-arabinonate dehydratase, go to the full flat file.
Reaction
Synonyms
2-keto-3-deoxyarabinoate/xylonate dehydratase, D-KDA dehydratase, KdaD, KDXD, KDXD/KDAD, saci_1939, Sso3118
ECTree
4.2.1.141 2-dehydro-3-deoxy-D-arabinonate dehydrataseAdvanced search results
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results (Substrates Products
Substrates Products on EC 4.2.1.141 - 2-dehydro-3-deoxy-D-arabinonate dehydratase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
-
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
key enzyme in degradation of D-arabinose
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
the enzyme is involved in the conversion of D-arabinose into the tricarboxylic acid cycle intermediate 2-oxoglutarate via the pentose oxidation pathway
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
the catalytic activity of the protein is investigated by performing indirect enzyme assays using arabinonate dehydratase with D-arabinonate as a substrate. A 50% decrease in the yield of 2-dehydro-3-deoxy-D-arabinonate is observed when both enzymes are co-incubated in the presence of Mg2+. Given the fact that D-arabinonate is converted to 2-oxoglutarate in D-arabinose cell-free extract, this enzyme is anticipated to be responsible for the dehydration of 2-dehydro-3-deoxy-D-arabinonate to the aldehyde 2,5-dioxopentanoate. Due to the unavailability of 2-dehydro-3-deoxy-D-arabinonate, it is not possible to show this in a direct enzyme assay. 2-Oxoglutarate is produced in an indirect assay using arabinonate dehydratase, the putative 2-dehydro-3-deoxy-D-arabinonate dehydratase and the predicted aldehyde dehydrogenase
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
-
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
key enzyme in degradation of D-arabinose
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
the enzyme is involved in the conversion of D-arabinose into the tricarboxylic acid cycle intermediate 2-oxoglutarate via the pentose oxidation pathway
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
the catalytic activity of the protein is investigated by performing indirect enzyme assays using arabinonate dehydratase with D-arabinonate as a substrate. A 50% decrease in the yield of 2-dehydro-3-deoxy-D-arabinonate is observed when both enzymes are co-incubated in the presence of Mg2+. Given the fact that D-arabinonate is converted to 2-oxoglutarate in D-arabinose cell-free extract, this enzyme is anticipated to be responsible for the dehydration of 2-dehydro-3-deoxy-D-arabinonate to the aldehyde 2,5-dioxopentanoate. Due to the unavailability of 2-dehydro-3-deoxy-D-arabinonate, it is not possible to show this in a direct enzyme assay. 2-Oxoglutarate is produced in an indirect assay using arabinonate dehydratase, the putative 2-dehydro-3-deoxy-D-arabinonate dehydratase and the predicted aldehyde dehydrogenase
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
-
-
-
?
2-dehydro-3-deoxy-D-arabinonate
2,5-dioxopentanoate + H2O
Sulfolobus acidocaldarius ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770
-
-
-
?
