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4.2.1.129: squalene-hopanol cyclase

This is an abbreviated version!
For detailed information about squalene-hopanol cyclase, go to the full flat file.

Reaction

hopan-22-ol
=
squalene
+
H2O

Synonyms

SHC, squalene-hopene cyclase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.129 squalene-hopanol cyclase

Reference

Reference on EC 4.2.1.129 - squalene-hopanol cyclase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sato, T.; Kouda, M.; Hoshino, T.
Site-directed mutagenesis experiments on the putative deprotonation site of squalene-hopene cyclase from Alicyclobacillus acidocaldarius
Biosci. Biotechnol. Biochem.
68
728-738
2004
Alicyclobacillus acidocaldarius
Manually annotated by BRENDA team
Hoshino, T.; Nakano, S.; Kondo, T.; Sato, T.; Miyoshi, A.
Squalene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring
Org. Biomol. Chem.
2
1456-1470
2004
Alicyclobacillus acidocaldarius
Manually annotated by BRENDA team
Siedenburg, G.; Jendrossek, D.
Squalene-hopene cyclases
Appl. Environ. Microbiol.
77
3905-3915
2011
Bradyrhizobium japonicum, Methylococcus capsulatus, no activity in Escherichia coli, Rhodopseudomonas palustris, Streptomyces peucetius, Tetrahymena thermophila, Zymomonas mobilis, Alicyclobacillus acidocaldarius (P33247)
Manually annotated by BRENDA team