4.2.1.129: squalene-hopanol cyclase

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For detailed information about squalene-hopanol cyclase, go to the full flat file.

Reaction

Synonyms

SHC, squalene-hopene cyclase

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.129 squalene-hopanol cyclase

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Results	in table
496	AA Sequence
3	Cloned(Commentary)
21	General Information
4	Inhibitors
13	kcat/KM [mM/s]
15	KM Value [mM]
3	Localization
7	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
10	Organism
4	Pathway
8	pH Optimum
1	pH Range
34	Protein Variants
2	Purification (Commentary)
8	Reaction
10	Reference
12	Substrates and Products (Substrate)
8	Subunits
16	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
13	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 4.2.1.129 - squalene-hopanol cyclase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate

Methylococcus capsulatus

-

i.e. CHAPS, almost complete inhibition

726715

sodium-taurodeoxycholate

Methylococcus capsulatus

-

almost complete inhibition

726715

additional information

2 entries

-

additional information

Methylococcus capsulatus

-

different glucopyranosides inhibit this enzyme more or less completely; no inhibition by Triton X-100 and Tween 80

726715

-

additional information

Rhodopseudomonas palustris

-

the enzyme is inhibited by detergents

726715

-