4.2.1.120: 4-hydroxybutanoyl-CoA dehydratase

This is an abbreviated version!
For detailed information about 4-hydroxybutanoyl-CoA dehydratase, go to the full flat file.

4-hydroxybutyryl-CoA dehydratase, 4-hydroxybutyryl-coenzyme A dehydratase, 4HBD, AbfD, Igni_0595, Msed_1321, Tneu_0422

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Results	in table
1	Activating Compound
290	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
12	Cofactor
1	Crystallization (Commentary)
2	Expression
8	General Information
1	General Stability
2	Inhibitors
1	kcat/KM [mM/s]
2	KM Value [mM]
2	Localization
4	Metals/Ions
4	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
18	Organism
4	Oxidation Stability
10	Pathway
2	pH Optimum
17	Protein Variants
4	Purification (Commentary)
6	Reaction
18	Reference
1	Renatured (Commentary)
10	Source Tissue
6	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
4	Subunits
11	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Turnover Number [1/s]

Inhibitors on EC 4.2.1.120 - 4-hydroxybutanoyl-CoA dehydratase

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Dithionite

inactivation, oxidation with potassium hexacyanoferrate(III) results in up to 84% reactivation

additional information

enzyme is not inactivated by 5 mM 4-nitrophenol, 5 mM chloramphenicol, and 5 mM hydroxylamine