4.2.1.12: phosphogluconate dehydratase
This is an abbreviated version!
For detailed information about phosphogluconate dehydratase, go to the full flat file.
Word Map on EC 4.2.1.12
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4.2.1.12
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entner-doudoroff
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aldolase
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2-keto-3-deoxy-6-phosphogluconate
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glucose-6-phosphate
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mobilis
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zymomonas
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kdpg
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gluconokinase
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4.1.2.14
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1.1.1.44
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synthesis
- 4.2.1.12
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entner-doudoroff
- aldolase
- 2-keto-3-deoxy-6-phosphogluconate
- glucose-6-phosphate
- mobilis
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zymomonas
- kdpg
- gluconokinase
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4.1.2.14
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1.1.1.44
- synthesis
Reaction
Synonyms
6-PG dehydrase, 6-phospho-D-gluconate dehydratase, 6-phosphogluconate dehydrase, 6-phosphogluconate dehydratase, 6-phosphogluconic dehydrase, 6PGDT, dehydratase, phosphogluconate, EDD, Edd protein, gluconate 6-phosphate dehydratase, gluconate-6-phosphate dehydratase, PGDH
ECTree
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Inhibitors
Inhibitors on EC 4.2.1.12 - phosphogluconate dehydratase
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glycerophosphates
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most strongly inhibited by the D-alpha-isomer which structurally corresponds to half of the substrate molecule
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the O2--sensitive target site is proposed to be an iron-sulfur cluster which is readily destroyed by oxidation
transcription of the edd gene and bacterial growth is lower if succinate is the sole carbon source, the edd mutant of Pseudomonas chlororaphis O6 fails to grow on glucose media
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additional information
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transcription of the edd gene and bacterial growth is lower if succinate is the sole carbon source, the edd mutant of Pseudomonas chlororaphis O6 fails to grow on glucose media
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