4.2.1.116: 3-hydroxypropionyl-CoA dehydratase

This is an abbreviated version!
For detailed information about 3-hydroxypropionyl-CoA dehydratase, go to the full flat file.

Word Map on EC 4.2.1.116

4.2.1.116

sedula

metallosphaera

3-hydroxypropionate/4-hydroxybutyrate

acryloyl-coa

thermoacidophilic

enoyl-coa

3-hydroxypropionate

sulfolobales

crenarchaeota

phylum

propionate

co2

succinate

semialdehyde

aurantiacus

chloroflexus

succinyl-coa

archaea

Reaction

Synonyms

3-hydroxypropionyl-CoA dehydratase, 3-hydroxypropionyl-coenzyme A dehydratase, 3HPCD, HPCD, Ms3HPCD, Msed_2001

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.116 3-hydroxypropionyl-CoA dehydratase

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Results	in table
190	AA Sequence
3	Cloned(Commentary)
1	Crystallization (Commentary)
11	General Information
4	KM Value [mM]
4	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
8	Organism
11	Pathway
6	PDB ID
2	pH Optimum
2	pH Range
1	Protein Variants
2	Purification (Commentary)
3	Reaction
6	Reference
3	Specific Activity [micromol/min/mg]
11	Substrates and Products (Substrate)
5	Subunits
16	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 4.2.1.116 - 3-hydroxypropionyl-CoA dehydratase

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3-hydroxypropionyl-CoA hydro-lyase

Catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea [1]. The enzyme from Metallosphaera sedula acts nearly equally as well on (S)-3-hydroxybutanoyl-CoA but not (R)-3-hydroxybutanoyl-CoA [2].