4.2.1.114: methanogen homoaconitase
This is an abbreviated version!
For detailed information about methanogen homoaconitase, go to the full flat file.
Reaction
Synonyms
CNAG_02565, HacA, HACN, Homoaconitase, LYS4, methanogen HACN, MJ1003, MJ1271, More
ECTree
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Engineering
Engineering on EC 4.2.1.114 - methanogen homoaconitase
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R26K
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the variant forms an relatively efficient isopropylmalate isomerase enzyme
R26V
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the variant forms an relatively efficient isopropylmalate isomerase enzyme
R26V/T27Y
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the variant resembles the MJ1277 isopropylmalate isomerase small subunit in its flexible loop sequence but demonstrates the broad substrate specificity of the R26V variant
T27A t
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the variant has uniformly lower specificity constants for both isopropylmalate isomerase and methanogen homoaconitase substrates
additional information
Cryptococcus neoformans var. grubii serotype A
generation of a CNAG_02565 deletion mutant, the deletion impairs mitochondrial functions, phenotype, overview
additional information
Cryptococcus neoformans var. grubii serotype A H99 / ATCC 208821 / CBS 10515 / FGSC 9487
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generation of a CNAG_02565 deletion mutant, the deletion impairs mitochondrial functions, phenotype, overview
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