4.2.1.109: methylthioribulose 1-phosphate dehydratase

This is an abbreviated version!
For detailed information about methylthioribulose 1-phosphate dehydratase, go to the full flat file.

Reaction

Synonyms

1-PMT-ribulose dehydratase, 5'-methylthioribulose-1-phosphate dehydratase, 5-Methylthioribulose-1-phosphate, 5-methylthioribulose-1-phosphate dehydratase, 5�-methylthioribulose-1-phosphate dehydratase, Apaf-1 interacting protein, Apaf-1-interacting protein, APIP, Mde1p, MtnB, MtnBD, MTRu-1-P dehydratase, MTRu-1-P dehydratase/enolase

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.109 methylthioribulose 1-phosphate dehydratase

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Results	in table
7813	AA Sequence
3	Cloned(Commentary)
1	Crystallization (Commentary)
16	Disease/ Diagnostics
10	General Information
1	KM Value [mM]
2	Localization
3	Metals/Ions
2	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
10	Organism
5	Pathway
4	PDB ID
3	pH Optimum
1	pH Range
7	Protein Variants
3	Purification (Commentary)
2	Reaction
2	Reaction Type
10	Reference
2	Source Tissue
12	Substrates and Products (Substrate)
2	Subunits
21	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 4.2.1.109 - methylthioribulose 1-phosphate dehydratase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

9 entries

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Bacillus subtilis

O31668

-

691391

the reaction product 5-(methylthio)-2,3-dioxopentyl phosphate is so labile that its chemical structure could not be isolated and analyzed

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Bacillus subtilis 168

O31668

-

691391

the reaction product 5-(methylthio)-2,3-dioxopentyl phosphate is so labile that its chemical structure could not be isolated and analyzed

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Homo sapiens

Q96GX9

substrate-binding mode, overview

730835

-

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Klebsiella pneumoniae

-

-

2660, 662095

-

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Klebsiella pneumoniae

-

the enzyme forms part of the methionine-salvage pathway

662095

-

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Rattus norvegicus

-

-

662095

-

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Rattus norvegicus

-

the enzyme forms part of the methionine-salvage pathway

662095

-

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Saccharomyces cerevisiae

P47095

enzyme of the methionine salvage pathway

692309

-

-

?

S-methyl-5-thio-D-ribulose 1-phosphate

5-(methylthio)-2,3-dioxopentyl phosphate + H2O

Tetrahymena thermophila

I7MAL0

activity of the MtnB domain

728615

-

-

?