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4.2.1.108: ectoine synthase

This is an abbreviated version!
For detailed information about ectoine synthase, go to the full flat file.

Word Map on EC 4.2.1.108

Reaction

(2S)-4-acetamido-2-aminobutanoate
=
L-ectoine
+
H2O

Synonyms

(Sa)Ect, EctC, ectoine synthase, L-ectoine synthase, SaEctC

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.108 ectoine synthase

Reference

Reference on EC 4.2.1.108 - ectoine synthase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Peters, P.; Galinski, E.A.; Trüper, H.G.
The biosynthesis of ectoine
FEMS Microbiol. Lett.
71
157-162
1990
Halorhodospira halochloris, Halomonas elongata
-
Manually annotated by BRENDA team
Ono, H.; Sawada, K.; Khunajakr, N.; Tao, T.; Yamamoto, M.; Hiramoto, M.; Shinmyo, A.; Takano, M.; Murooka, Y.
Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata
J. Bacteriol.
181
91-99
1999
Halomonas elongata, Halomonas elongata OUT30018
Manually annotated by BRENDA team
Kuhlmann, A.U.; Bremer, E.
Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp.
Appl. Environ. Microbiol.
68
772-783
2002
Alkalihalobacillus alcalophilus, Virgibacillus pantothenticus, Sporosarcina psychrophila, no activity in Bacillus cereus, no activity in Bacillus circulans, no activity in Bacillus licheniformis, no activity in Bacillus megaterium, no activity in Bacillus subtilis, Virgibacillus salexigens, no activity in Bacillus thuringiensis, no activity in Aneurinibacillus aneurinilyticus, no activity in Paenibacillus polymyxa, Sporosarcina pasteurii (Q9AP33), Sporosarcina pasteurii, Chromohalobacter salexigens (Q9ZEU6), no activity in Bacillus cereus DSM 31, no activity in Aneurinibacillus aneurinilyticus DSM 5562, no activity in Bacillus subtilis JH642
Manually annotated by BRENDA team
Reshetnikov, A.S.; Khmelenina, V.N.; Trotsenko, Y.A.
Characterization of the ectoine biosynthesis genes of haloalkalotolerant obligate methanotroph "Methylomicrobium alcaliphilum 20Z"
Arch. Microbiol.
184
286-297
2006
Methylotuvimicrobium alcaliphilum (Q4JQJ3)
Manually annotated by BRENDA team
Louis, P.; Galinski, E.A.
Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli
Microbiology
143
1141-1149
1997
Marinococcus halophilus (O06061), Marinococcus halophilus
Manually annotated by BRENDA team
Nakayama, H.; Yoshida, K.; Ono, H.; Murooka, Y.; Shinmyo, A.
Ectoine, the compatible solute of Halomonas elongata, confers hyperosmotic tolerance in cultured tobacco cells
Plant Physiol.
122
1239-1247
2000
Halomonas elongata, no activity in Nicotiana tabacum, Halomonas elongata OUT30018
Manually annotated by BRENDA team
Rajan, L.A.; Joseph, T.C.; Thampuran, N.; James, R.; Chinnusamy, V.; Bansal, K.C.
Characterization and phylogenetic analysis of ectoine biosynthesis genes from Bacillus halodurans
Arch. Microbiol.
190
481-487
2008
Halalkalibacterium halodurans (A5A5G3), Halalkalibacterium halodurans TCJAR021 (A5A5G3)
Manually annotated by BRENDA team
Rajan, L.A.; Joseph, T.C.; Thampuran, N.; James, R.; Kumar, K.A.; Viswanathan, C.; Bansal, K.C.
Cloning and heterologous expression of ectoine biosynthesis genes from Bacillus halodurans in Escherichia coli
Biotechnol. Lett.
30
1403-1407
2008
Halalkalibacterium halodurans (A5A5G3), Halalkalibacterium halodurans TCJAR021 (A5A5G3)
Manually annotated by BRENDA team
Witt, E.M.; Davies, N.W.; Galinski, E.A.
Unexpected property of ectoine synthase and its application for synthesis of the engineered compatible solute ADPC
Appl. Microbiol. Biotechnol.
91
113-122
2011
Halomonas elongata, Halomonas elongata DSM 2581
Manually annotated by BRENDA team
Reshetnikov, A.S.; Khmelenina, V.N.; Mustakhimov, I.I.; Kalyuzhnaya, M.; Lidstrom, M.; Trotsenko, Y.A.
Diversity and phylogeny of the ectoine biosynthesis genes in aerobic, moderately halophilic methylotrophic bacteria
Extremophiles
15
653-663
2011
Methylophaga thalassica (A9YZX7), Methylophaga thalassica, Methylophaga alcalica (A9YZY2), Methylobacter marinus (B2CKR7), Methylotuvimicrobium alcaliphilum (B2CKS1), Methylarcula marina (D2KPJ4), Methylarcula marina, Methylotuvimicrobium kenyense (Q307N7), Methylotuvimicrobium kenyense, Methylotuvimicrobium alcaliphilum ML1 (B2CKS1), Methylobacter marinus 7C (B2CKR7), Methylobacter marinus 7C, Methylophaga thalassica ATCC 33146 (A9YZX7), Methylophaga alcalica M8 (A9YZY2), Methylophaga alcalica M8, Methylotuvimicrobium kenyense AMO1 (Q307N7), Methylarcula marina ML1 (D2KPJ4)
Manually annotated by BRENDA team
Kobus, S.; Widderich, N.; Hoeppner, A.; Bremer, E.; Smits, S.
Overproduction, crystallization and X-ray diffraction data analysis of ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis
Acta Crystallogr. Sect. F
71
1027-1032
2015
Sphingopyxis alaskensis (Q1GNW6), Sphingopyxis alaskensis, Sphingopyxis alaskensis DSM 13593 / LMG 18877 / RB2256 (Q1GNW6)
Manually annotated by BRENDA team
Widderich, N.; Kobus, S.; Hoeppner, A.; Riclea, R.; Seubert, A.; Dickschat, J.S.; Heider, J.; Smits, S.H.; Bremer, E.
Biochemistry and crystal structure of ectoine synthase a metal-containing member of the cupin superfamily
PLoS ONE
11
e0151285
2016
Sphingopyxis alaskensis (Q1GNW6), Sphingopyxis alaskensis, Sphingopyxis alaskensis DSM 13593 / LMG 18877 / RB2256 (Q1GNW6)
Manually annotated by BRENDA team
Anburajan, L.; Meena, B.; Vinithkumar, N.; Kirubagaran, R.; Dharani, G.
Functional characterization of a major compatible solute in Deep Sea halophilic eubacteria of active volcanic Barren Island, Andaman and Nicobar Islands, India
Infect. Genet. Evol.
73
261-265
2019
Alkalihalobacillus clausii (MH020164), Alkalihalobacillus clausii, Alkalihalobacillus clausii NIOT-DSB04 (MH020164)
Manually annotated by BRENDA team