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4.2.1.105: 2-hydroxyisoflavanone dehydratase

This is an abbreviated version!
For detailed information about 2-hydroxyisoflavanone dehydratase, go to the full flat file.

Word Map on EC 4.2.1.105

Reaction

2,4',5,7-tetrahydroxyisoflavanone
=
genistein
+
H2O

Synonyms

2,7,4'-trihydroxyisoflavanone dehydratase, 2-hydroxyisoflavanone dehydratase, GmHID, HID, HIDH, hydroxyisoflavanone dehydratase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.105 2-hydroxyisoflavanone dehydratase

Substrates Products

Substrates Products on EC 4.2.1.105 - 2-hydroxyisoflavanone dehydratase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,5,7,4'-tetrahydroxyisoflavanone
?
show the reaction diagram
-
flavonoid metabolism in hairy root cultures of Lotus japonicus, control plants and plants overexpressing 2-hydroxyisoflavanone
accumulation of daidzein and genistein in overexpressors indicating that 2-hydroxyisoflavanone dehydratase is a critical determinant of isoflavone productivity, production of coumestrol in control plants and in plants overexpressing 2-hydroxyisoflavanone dehydratase, production of isoliquiritigenin and liquiritigenin in overexpressors of 2-hydroxyisoflavanone
-
?
2,5,7,4'-tetrahydroxyisoflavanone
genistein + H2O
show the reaction diagram
2,7,4'-trihydroxyisoflavanone
daidzein + H2O
show the reaction diagram
2,7-dihydroxy-4'-methoxyisoflavanone
formononetin + H2O
show the reaction diagram
p-nitrophenyl butyrate
?
show the reaction diagram
activity is 0.6% of the activity with 2,5,7,4'-tetrahydroxyisoflavanone
-
-
?
additional information
?
-
-
2-hydroxyisoflavanone dehydratase is a critical determinant of isoflavone productivity in hairy root cultures of Lotus japonicus
-
-
?