4.1.99.13: (6-4)DNA photolyase
This is an abbreviated version!
For detailed information about (6-4)DNA photolyase, go to the full flat file.
Word Map on EC 4.1.99.13
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4.1.99.13
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photoproducts
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cyclobutane
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uv-induced
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cryptochromes
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photoreactivation
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light-dependent
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pyrimidone
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blue-light
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photorepair
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oxetane
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pyrimidine-pyrimidone
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photoreduction
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photolesion
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dash
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ostreococcus
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four-membered
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fadox
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photoreception
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cry-dashs
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dewar
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cryptochrome-dash
- 4.1.99.13
- photoproducts
-
cyclobutane
-
uv-induced
-
cryptochromes
-
photoreactivation
-
light-dependent
-
pyrimidone
-
blue-light
-
photorepair
-
oxetane
-
pyrimidine-pyrimidone
-
photoreduction
-
photolesion
-
dash
- ostreococcus
-
four-membered
- fadox
-
photoreception
- cry-dashs
-
dewar
- cryptochrome-dash
Reaction
= 2 pyrimidine residues (in DNA)
Synonyms
(6-4) DNA photolyase, (6-4) photolyase, (6-4) PHR, (6-4) PL, (6-4) PP-specific PL, (6-4)-Phr, (6-4)photolyase, 6-4 DNA photolyase, 6-4 photolyase, 6-4CiPhr, 6-4PP-photolyase, animal (6-4) photolyase, At64, At64PHR, bacterial (6-4) photolyase, CmPHR1, Cry1, CryB, deoxyribodipyrimidine photolyase-related protein, Dm64, DNA photolyase, Ds64PHR, H64PRH, human (6-4) photolyase homologous protein, NF-10, OtCPF1, phr (6-4), PhrB, PL-(6-4), prokaryotic (6-4) photolyase, RSP_3077, TRIREDRAFT_77473, XELAEV_18035355mg, Xl64phr
ECTree
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Source Tissue
Source Tissue on EC 4.1.99.13 - (6-4)DNA photolyase
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by Northern blot analysis it is demonstrated that the transcript is expressed at highest level only in adult ovary
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exposure of the cells to blue light, but not red light, for 12 h results in more than 20fold increase of the (6-4) photolyase mRNA
additional information
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testes exhibit very high basal expression values in the F1 interspecies hybrid for photolyase 6-4 about 100fold higher than liver
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testes exhibit very high basal expression values in the F1 interspecies hybrid for photolyase 6-4 about 100fold higher than liver
gene is strongly expressed in the upper part of the animal and not in the middle part or the base
additional information
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gene is strongly expressed in the upper part of the animal and not in the middle part or the base
additional information
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it is found that the 6-4 photoreactivating activity is constitutively expressed prior to as well as during the period of repair
additional information
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expression levels of (64) photolyase in 24 h dark-maintained algae increase rapidly after 8-h exposure to white light, and also increase after being treated with NaCl for 8 h
additional information
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by Northern blot analysis an ubiquitous expression pattern is demonstrated
additional information
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by Northern blot analysis it is demonstrated that the transcript is expressed in multiple tissues
additional information
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immunoblot analysis using a monoclonal antibody reveals that the NF-10 protein is expressed in cell lines from all complementation groups of xeroderma pigmentosum
additional information
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tissue expression pattern, overview. The expression of 6-4 photolyase in F1 interspecies hybrids appears to be about 3-4fold above the parental line expression in the skin and eyes. In the brain and gill, the F1 interspecies hybrid 6-4 photolyase expression is similar to that of Xiphophorus couchianus, and both the F1 and Xiphophorus couchianus exhibit a greater than 5fold higher basal expression in the heart compared to Xiphophorus maculatus. The 6-4 photolyase becomes dramatically dysregulated in testis compared to either parent exhibiting substantial upregulated basal expression (over 30fold compared to Xiphophoruscouchianus and over 50fold for Xiphophorus maculatus). Liver shows much reduced 6-4 basal expression
additional information
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tissue expression pattern, overview. The expression of 6-4 photolyase in F1 interspecies hybrids appears to be about 3-4fold above the parental line expression in the skin and eyes. In the brain and gill, the F1 interspecies hybrid 6-4 photolyase expression is similar to that of Xiphophorus couchianus, and both the F1 and Xiphophorus couchianus exhibit a greater than 5fold higher basal expression in the heart compared to Xiphophorus maculatus. The 6-4 photolyase becomes dramatically dysregulated in testis compared to either parent exhibiting substantial upregulated basal expression (over 30fold compared to Xiphophoruscouchianus and over 50fold for Xiphophorus maculatus). Liver shows much reduced 6-4 basal expression