4.1.3.B3: 4-carboxy-4-hydroxy-2-oxoadipate aldolase
This is an abbreviated version!
For detailed information about 4-carboxy-4-hydroxy-2-oxoadipate aldolase, go to the full flat file.
Reaction
Synonyms
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase, 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolase, CHA aldolase, HMG/CHA aldolase, PmdF
ECTree
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Metals Ions
Metals Ions on EC 4.1.3.B3 - 4-carboxy-4-hydroxy-2-oxoadipate aldolase
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Mg2+
additional information
the enzyme is a class II divalent metal ion-dependent aldolase. Coordination of a metal ion to support the binding of a pyruvyl moiety in the class II aldolase is essential, metal binding Glu199 residue
Mg2+
a magnesium ion is coordinated directly or indirectly via water through interactions with Asp102, Asp124, and Glu199