4.1.3.43: 4-hydroxy-2-oxohexanoate aldolase
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For detailed information about 4-hydroxy-2-oxohexanoate aldolase, go to the full flat file.
Reaction
Synonyms
BphI, TTHB246
ECTree
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Systematic Name
Systematic Name on EC 4.1.3.43 - 4-hydroxy-2-oxohexanoate aldolase
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(S)-4-hydroxy-2-oxohexanoate pyruvate-lyase (propanal-forming)
Requires Mn2+ for maximal activity [1,2]. The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 4.1.3.39, 4-hydroxy-2-oxovalerate aldolase [1,2,6]. The enzyme forms a bifunctional complex with EC 1.2.1.87, propanal dehydrogenase (CoA-propanoylating), with a tight channel connecting the two subunits [3,4,6].