4.1.3.38: aminodeoxychorismate lyase

This is an abbreviated version!
For detailed information about aminodeoxychorismate lyase, go to the full flat file.

Reaction

Synonyms

4-amino-4-deoxychorismate lyase, Abz2, ADC lyase, ADCL, ADCS, aminodeoxychorismate lyase, aminodeoxychorismate synthase, enzyme X, PabC, PabC-1, PabC-2, TTHA0621 protein

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.3 Oxo-acid-lyases

4.1.3.38 aminodeoxychorismate lyase

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Results	in table
5093	AA Sequence
1	Application
1	CAS Registry Number
10	Cloned(Commentary)
11	Cofactor
4	Crystallization (Commentary)
7	General Information
2	Inhibitors
2	Localization
6	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
23	Organism
5	Pathway
5	PDB ID
1	pH Optimum
8	Protein Variants
9	Purification (Commentary)
4	Reaction
1	Reaction Type
21	Reference
24	Substrates and Products (Substrate)
5	Subunits
37	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

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Application on EC 4.1.3.38 - aminodeoxychorismate lyase

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drug development

Pseudomonas aeruginosa

Q9HZN6

the absence of the enzyme in humans and its essentiality in various microbes suggests that inhibition of PabC offers the possibility of therapeutics targeting a range of microbial infections, potential of this protein for early stage drug discovery

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