4.1.3.3: N-acetylneuraminate lyase

This is an abbreviated version!
For detailed information about N-acetylneuraminate lyase, go to the full flat file.

Word Map on EC 4.1.3.3

4.1.3.3

mannac

2-epimerase

n-acetylmannosamine

aldolases

n-glycolylneuraminic

cmp-sialic

dihydrodipicolinate

3.2.1.18

biotechnology

neu5gc

dhdps

synthesis

n-acylneuraminate

analysis

industry

Reaction

Synonyms

Acetylneuraminate pyruvate-lyase, class I NAL, EcNanA, Lyase, acetylneuraminate, N-acetyl-d-neuraminic acid aldolase, N-acetyl-D-neuraminic acid lyase, N-Acetylneuraminate aldolase, N-Acetylneuraminate lyase, N-acetylneuraminate pyruvate lyase, N-Acetylneuraminate pyruvate-lyase, N-Acetylneuraminic acid aldolase, N-Acetylneuraminic acid lyase, N-Acetylneuraminic aldolase, N-Acetylneuraminic lyase, NAL, NALase, NanA, NANA lyase, Neu5Ac aldolase, Neu5Ac lyase, NeuAc aldolase, NeuAc lyase, Neuraminate aldolase, Neuraminic acid aldolase, Neuraminic aldolase, NPL, PmNanA, sialate aldolase, Sialate lyase, sialate-pyruvate lyase, Sialic acid aldolase, Sialic aldolase

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.3 Oxo-acid-lyases

4.1.3.3 N-acetylneuraminate lyase

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Results	in table
4	Activating Compound
2595	AA Sequence
14	Application
1	CAS Registry Number
31	Cloned(Commentary)
12	Crystallization (Commentary)
16	Disease/ Diagnostics
4	Expression
6	General Information
3	General Stability
92	Inhibitors
57	kcat/KM [mM/s]
5	Ki Value [mM]
160	KM Value [mM]
3	Localization
14	Metals/Ions
36	Molecular Weight [Da]
34	Natural Substrates/ Products (Substrates)
132	Organism
3	Oxidation Stability
6	Pathway
213	PDB ID
35	pH Optimum
9	pH Range
6	pH Stability
3	pI Value
105	Protein Variants
37	Purification (Commentary)
8	Reaction
8	Reaction Type
91	Reference
1	Renatured (Commentary)
16	Source Tissue
29	Specific Activity [micromol/min/mg]
1	Storage Stability
186	Substrates and Products (Substrate)
31	Subunits
96	Synonyms
1	Systematic Name
31	Temperature Optimum [°C]
2	Temperature Range [°C]
32	Temperature Stability [°C]
111	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 4.1.3.3 - N-acetylneuraminate lyase

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N-acetyl-D-mannosamine + pyruvate

N-acetylneuraminate

4 entries

N-acetyl-D-neuraminic acid

N-acetyl-D-mannosamine + pyruvate

2 entries

N-Acetylmannosamine + pyruvate

2 entries

N-acetylneuraminate

N-acetyl-D-mannosamine + pyruvate

19 entries

N-Acetylneuraminic acid

6 entries

N-Acetylneuraminic acid

N-Acetyl-D-mannosamine + pyruvate

Homo sapiens

regulation of sialic acid metabolism

652833