4.1.3.27: anthranilate synthase

This is an abbreviated version!
For detailed information about anthranilate synthase, go to the full flat file.

Word Map on EC 4.1.3.27

4.1.3.27

amidotransferase

feedback-insensitive

trpeg

l-tryptophan

p-aminobenzoate

isochorismate

catharanthus

roseus

glutamine-dependent

5-methyltryptophan

feedback-resistant

chorismate-utilizing

tryptamine

paba

buchnera

prephenate

indole-3-glycerol

4-amino-4-deoxychorismate

indoleglycerol

5-phosphoribosylpyrophosphate

aminodeoxychorismate

biotechnology

synthesis

molecular biology

medicine

Reaction

Synonyms

ANTA synthase, anthranilate synthase, anthranilate synthase a1, anthranilate synthase alpha 1, anthranilate synthase alpha 2, anthranilate synthase alpha2, anthranilate synthase component I, anthranilate synthase-phosphoribosyltransferase, anthranilate synthetase, AS-I, ASA, ASA1, ASA2, ASalpha, ASalphabeta, ASalphabeta-1, ASB, ASB1, CaASA1, CaASA2, chorismate lyase, Glutamine amido-transferase, Glutamine amidotransferase, HvASa2, OASA, OASA1, OASA1D, OASA2, PhnAB, PhnAB anthranilate synthase, synthase, anthranilate, synthetase, anthranilate, TrpDE, TrpE, TrpED

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.3 Oxo-acid-lyases

4.1.3.27 anthranilate synthase

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Results	in table
8	Activating Compound
42078	AA Sequence
10	Application
1	CAS Registry Number
38	Cloned(Commentary)
6	Crystallization (Commentary)
3	Expression
17	General Information
2	General Stability
2	IC50 Value
174	Inhibitors
55	Ki Value [mM]
87	KM Value [mM]
8	Localization
33	Metals/Ions
74	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
204	Organism
9	Pathway
23	PDB ID
27	pH Optimum
3	pH Range
2	pI Value
50	Protein Variants
31	Purification (Commentary)
8	Reaction
6	Reaction Type
131	Reference
27	Source Tissue
23	Specific Activity [micromol/min/mg]
7	Storage Stability
150	Substrates and Products (Substrate)
57	Subunits
78	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Range [°C]
10	Temperature Stability [°C]
26	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 4.1.3.27 - anthranilate synthase

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Thermococcus kodakarensis

Q9YGB3

649565

6.7

Ogataea henricii

Gln-dependent reaction

33291

7.2 - 7.6

Streptomyces sp.

Gln-dependent activity

33293

7.3

Ogataea henricii

NH4+-dependent enzyme

33291

7.3 - 8

Ailanthus altissimus

isoenzyme AS-b

33301

7.5

Streptomyces venezuelae

748650

7.5 - 8.3

Catharanthus roseus

Gln-dependent activity

33305

7.6

2 entries

7.8

Claviceps sp.

Gln-dependent activity

33288

3 entries

8.1

Archaeoglobus fulgidus

L-Gln-dependent reaction, with 25% glycerol and 2 M KCl

664871

8.5

3 entries

8.6

Claviceps sp.

NH4+-dependent activity

33288

8.7

2 entries

8.8

2 entries

additional information

Streptomyces sp.

NH4+-dependent activity increases linearly through pH 9.0 without reaching a maximum

33293