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4.1.3.27: anthranilate synthase

This is an abbreviated version!
For detailed information about anthranilate synthase, go to the full flat file.

Word Map on EC 4.1.3.27

Reaction

chorismate
+
L-glutamine
=
anthranilate
 +
pyruvate
 +
L-glutamate

Synonyms

ANTA synthase, anthranilate synthase, anthranilate synthase a1, anthranilate synthase alpha 1, anthranilate synthase alpha 2, anthranilate synthase alpha2, anthranilate synthase component I, anthranilate synthase-phosphoribosyltransferase, anthranilate synthetase, AS-I, ASA, ASA1, ASA2, ASalpha, ASalphabeta, ASalphabeta-1, ASB, ASB1, CaASA1, CaASA2, chorismate lyase, Glutamine amido-transferase, Glutamine amidotransferase, HvASa2, OASA, OASA1, OASA1D, OASA2, PhnAB, PhnAB anthranilate synthase, synthase, anthranilate, synthetase, anthranilate, TrpDE, TrpE, TrpED

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.27 anthranilate synthase

Temperature Stability

Temperature Stability on EC 4.1.3.27 - anthranilate synthase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25 - 85
-
activity steadily increases with the rising of temperature in the range 25°C to 85°C, the enzyme is fully active above 85°C
35
-
5 min, about 25% loss of activity
40
-
5 min, about 50% loss of activity
45
-
5 min, about 80% loss of activity
50
-
5 min, about 90% loss of activity
75
-
half-life in presence of 25% glycerol without KCl: 4.6 min, in 25% glycerol with 2 M KCl activity is constant for over 4 h after initial drop in activity to 83%
80
-
half-life in presence of 25% glycerol without KCl: 1.2 min, half-life in presence of 25% glycerol and 2 M KCl: 200 min
85
-
half-life in presence of 25% glycerol without KCl: 0.9 min, half-life in presence of 25% glycerol and 2 M KCl: 50 min
90
-
half-life in presence of 25% glycerol and 2 M KCl: 12 min
95
-
half-life in presence of 25% glycerol and 2 M KCl: 4.1 min