4.1.3.27: anthranilate synthase

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For detailed information about anthranilate synthase, go to the full flat file.

Reaction

Synonyms

ANTA synthase, anthranilate synthase, anthranilate synthase a1, anthranilate synthase alpha 1, anthranilate synthase alpha 2, anthranilate synthase alpha2, anthranilate synthase component I, anthranilate synthase-phosphoribosyltransferase, anthranilate synthetase, AS-I, ASA, ASA1, ASA2, ASalpha, ASalphabeta, ASalphabeta-1, ASB, ASB1, CaASA1, CaASA2, chorismate lyase, Glutamine amido-transferase, Glutamine amidotransferase, HvASa2, OASA, OASA1, OASA1D, OASA2, PhnAB, PhnAB anthranilate synthase, synthase, anthranilate, synthetase, anthranilate, TrpDE, TrpE, TrpED

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.3 Oxo-acid-lyases

                4.1.3.27 anthranilate synthase

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Results	in table
8	Activating Compound
42078	AA Sequence
10	Application
1	CAS Registry Number
38	Cloned(Commentary)
6	Crystallization (Commentary)
3	Expression
17	General Information
2	General Stability
2	IC50 Value
174	Inhibitors
55	Ki Value [mM]
87	KM Value [mM]
8	Localization
33	Metals/Ions
74	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
204	Organism
9	Pathway
23	PDB ID
27	pH Optimum
3	pH Range
2	pI Value
50	Protein Variants
31	Purification (Commentary)
8	Reaction
6	Reaction Type
131	Reference
27	Source Tissue
23	Specific Activity [micromol/min/mg]
7	Storage Stability
150	Substrates and Products (Substrate)
57	Subunits
78	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Range [°C]
10	Temperature Stability [°C]
26	Turnover Number [1/s]

General Stability

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General Stability on EC 4.1.3.27 - anthranilate synthase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

1 mM dithiothreitol and 50 mM L-glutamine have a stabilizing effect each

Saccharolobus solfataricus

-

677906

anthranilate synthetase activity of the enzyme complex is quite unstable unless Gln, MgCl2, Tris and glycerol are included in the extraction buffer

Claviceps sp.

-

33290