4.1.3.17: 4-hydroxy-4-methyl-2-oxoglutarate aldolase

This is an abbreviated version!
For detailed information about 4-hydroxy-4-methyl-2-oxoglutarate aldolase, go to the full flat file.

Reaction

Synonyms

4-hydroxy-4-methyl-2-ketoglutarate aldolase, 4-hydroxy-4-methyl-2-oxoglutarate aldolase, 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolase, aldolase, 4-hydroxy-4-methyl-2-oxoglutarate, gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase, HMG aldolase, HMG/CHA aldolase, KDPG aldolase, MHK aldolase, MHKG aldolase, pyruvate aldolase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.3 Oxo-acid-lyases

                4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase

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Results	in table
3	Activating Compound
10314	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
6	General Information
20	Inhibitors
34	kcat/KM [mM/s]
4	Ki Value [mM]
52	KM Value [mM]
31	Metals/Ions
9	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
106	Organism
11	Pathway
1	PDB ID
20	pH Optimum
2	pH Range
1	pH Stability
2	pI Value
11	Protein Variants
7	Purification (Commentary)
2	Reaction
1	Reaction Type
17	Reference
2	Source Tissue
5	Specific Activity [micromol/min/mg]
1	Storage Stability
49	Substrates and Products (Substrate)
6	Subunits
18	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
35	Turnover Number [1/s]

Organism

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Organism on EC 4.1.3.17 - 4-hydroxy-4-methyl-2-oxoglutarate aldolase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Arachis hypogaea

-

4971, 33187

-

-

brenda

Comamonas testosteroni

-

33189

-

-

brenda

Escherichia coli

development of a selection strategy for the evolution of the substrate specificity of KDPG aldolase based on a pyruvate kinase-deficient strain of Escherichia coli

664301

-

-

brenda

Pseudomonas putida

2 entries

Pseudomonas straminea

-

33192, 33193, 33194, 650628

-

-

brenda

Pseudomonas straminea NGJ1

-

650628

-

-

brenda

Saccharomyces cerevisiae

-

727049

-

-

brenda

Thermus thermophilus

-

727049

-

-

brenda

Thermus thermophilus HB8 / ATCC 27634 / DSM 579

-

727049

-

-

brenda

Pseudomonas putida

-

33188, 33191, 715556, 727049

-

-

brenda

Pseudomonas putida

-

749095

A5W059

UniProt

brenda