4.1.3.17: 4-hydroxy-4-methyl-2-oxoglutarate aldolase
This is an abbreviated version!
For detailed information about 4-hydroxy-4-methyl-2-oxoglutarate aldolase, go to the full flat file.
Reaction
Synonyms
4-hydroxy-4-methyl-2-ketoglutarate aldolase, 4-hydroxy-4-methyl-2-oxoglutarate aldolase, 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolase, aldolase, 4-hydroxy-4-methyl-2-oxoglutarate, gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase, HMG aldolase, HMG/CHA aldolase, KDPG aldolase, MHK aldolase, MHKG aldolase, pyruvate aldolase
ECTree
Advanced search results
KM Value
KM Value on EC 4.1.3.17 - 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
0.071
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C
0.15
2-hydroxy-4-oxopentanedioic acid
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C
0.015
wild type enzyme, in the absence of phosphate, at pH 8.0 and 25°C
0.104
4-carboxy-4-hydroxy-2-oxoadipate
wild type enzyme, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
8.8
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C
25
4-hydroxy-2-oxopentanoate
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C
0.022
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C
0.1265
4-hydroxy-4-methyl-2-oxoglutarate
-
pH 8.0, 25°C, RraA-like protein Yer010Cp
0.1507
4-hydroxy-4-methyl-2-oxoglutarate
-
pH 8.0, 25°C, RraA-like protein TtRraA
0.188
4-hydroxy-4-methyl-2-oxoglutarate
wild type enzyme, in the absence of phosphate, at pH 8.0 and 25°C
0.26
4-hydroxy-4-methyl-2-oxoglutarate
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C
0.304
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R40A, in the absence of phosphate, at pH 8.0 and 25°C
0.389
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme H75A, in the absence of phosphate, at pH 8.0 and 25°C
0.796
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme N71A, in the absence of phosphate, at pH 8.0 and 25°C
1.08
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme T145A, in the absence of phosphate, at pH 8.0 and 25°C
1.11
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme N71A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
1.21
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme H75A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
1.36
4-hydroxy-4-methyl-2-oxoglutarate
wild type enzyme, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
1.37
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R195A, in the absence of phosphate, at pH 8.0 and 25°C
1.39
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme G144V, in the absence of phosphate, at pH 8.0 and 25°C
1.78
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme T145A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
2.01
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme K147A, in the absence of phosphate, at pH 8.0 and 25°C
2.89
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R195A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
3.21
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R123K, in the absence of phosphate, at pH 8.0 and 25°C
3.26
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R40A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
3.72
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme K147A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
3.97
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R123K, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
5.5
4-hydroxy-4-methyl-2-oxoglutarate
-
R123K mutant protein, pH 8.0, 25°C
6.83
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme G144V, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
0.036
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C; substrate inhibition constante 0.25 mM
0.298
oxaloacetate
wild type enzyme, in the absence of phosphate, at pH 8.0 and 25°C
0.3
oxaloacetate
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C; substrate inhibition constante 0.37 mM
0.741
oxaloacetate
wild type enzyme, in the presence of 2 mM phosphate, at pH 8.0 and 25°C