4.1.3.17: 4-hydroxy-4-methyl-2-oxoglutarate aldolase
This is an abbreviated version!
For detailed information about 4-hydroxy-4-methyl-2-oxoglutarate aldolase, go to the full flat file.
Reaction
Synonyms
4-hydroxy-4-methyl-2-ketoglutarate aldolase, 4-hydroxy-4-methyl-2-oxoglutarate aldolase, 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolase, aldolase, 4-hydroxy-4-methyl-2-oxoglutarate, gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase, HMG aldolase, HMG/CHA aldolase, KDPG aldolase, MHK aldolase, MHKG aldolase, pyruvate aldolase
ECTree
Advanced search results
KCat KM Value
KCat KM Value on EC 4.1.3.17 - 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
0.38
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C
3.5
2-hydroxy-4-oxopentanedioic acid
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C
893
wild type enzyme, in the absence of phosphate, at pH 8.0 and 25°C
1400
4-carboxy-4-hydroxy-2-oxoadipate
wild type enzyme, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
0.0019
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C
0.022
4-hydroxy-2-oxopentanoate
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C
0.00645
mutant enzyme K147A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
0.00697
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme K147A, in the absence of phosphate, at pH 8.0 and 25°C
0.0165
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme N71A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
0.0176
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme N71A, in the absence of phosphate, at pH 8.0 and 25°C
0.0176
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R123K, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
0.0267
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R123K, in the absence of phosphate, at pH 8.0 and 25°C
0.0577
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme G144V, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
0.155
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme G144V, in the absence of phosphate, at pH 8.0 and 25°C
0.823
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme T145A, in the absence of phosphate, at pH 8.0 and 25°C
3.98
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R195A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
4.91
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R195A, in the absence of phosphate, at pH 8.0 and 25°C
6.01
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme T145A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
11.2
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R40A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
22
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme R40A, in the absence of phosphate, at pH 8.0 and 25°C
44.5
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme H75A, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
57.3
4-hydroxy-4-methyl-2-oxoglutarate
mutant enzyme H75A, in the absence of phosphate, at pH 8.0 and 25°C
74
4-hydroxy-4-methyl-2-oxoglutarate
-
wild type protein, 1.0 mM Mg2+, pH 8.0, 25°C
83
4-hydroxy-4-methyl-2-oxoglutarate
wild type enzyme, in the absence of phosphate, at pH 8.0 and 25°C
98.5
4-hydroxy-4-methyl-2-oxoglutarate
wild type enzyme, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
210
4-hydroxy-4-methyl-2-oxoglutarate
-
pH 8.0, 25°C, RraA-like protein Yer010Cp
620
4-hydroxy-4-methyl-2-oxoglutarate
-
wild type protein, 1.0 mM Mn2+, pH 8.0, 25°C
2400
4-hydroxy-4-methyl-2-oxoglutarate
-
pH 8.0, 25°C, RraA-like protein TtRraA
4.26
wild type enzyme, in the presence of 2 mM phosphate, at pH 8.0 and 25°C
6.24
oxaloacetate
wild type enzyme, in the absence of phosphate, at pH 8.0 and 25°C