4.1.3.16: 4-Hydroxy-2-oxoglutarate aldolase

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For detailed information about 4-Hydroxy-2-oxoglutarate aldolase, go to the full flat file.

Reaction

Synonyms

2-keto-4-hydroxybutyrate aldolase, 2-keto-4-hydroxyglutarate aldolase, 2-keto-4-hydroxyglutaric aldolase, 2-oxo-3-deoxy-6-phosphogluconate aldolase, 2-oxo-4-hydroxyglutarate aldolase, 2-oxo-4-hydroxyglutaric aldolase, 4-hydroxy-2-ketoglutarate aldolase, 4-hydroxy-2-ketoglutaric aldolase, 4-hydroxy-2-oxoglutarate aldolase, aldolase, 4-hydroxy-2-oxoglutarate, DHDPSL, dihydrodipicolinate synthase-like enzyme, DL-4-Hydroxy-2-ketoglutarate aldolase, EC 4.1.2.1, EC 4.1.2.31, eda, Entner-Doudoroff aldolase, hOGA, HOGA1, hydroxyketoglutarate aldolase, Hydroxyketoglutaric aldolase, KDPGlc aldolase, KHG-aldolase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.3 Oxo-acid-lyases

                4.1.3.16 4-Hydroxy-2-oxoglutarate aldolase

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Results	in table
4	Activating Compound
6473	AA Sequence
2	Application
1	CAS Registry Number
5	Cloned(Commentary)
2	Crystallization (Commentary)
80	Disease/ Diagnostics
4	General Information
1	General Stability
48	Inhibitors
10	kcat/KM [mM/s]
3	Ki Value [mM]
33	KM Value [mM]
4	Localization
12	Metals/Ions
16	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
21	Organism
6	Pathway
38	PDB ID
6	pH Optimum
5	pH Range
23	Protein Variants
10	Purification (Commentary)
1	Reaction
2	Reaction Type
20	Reference
13	Source Tissue
12	Specific Activity [micromol/min/mg]
4	Storage Stability
50	Substrates and Products (Substrate)
8	Subunits
26	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 4.1.3.16 - 4-Hydroxy-2-oxoglutarate aldolase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

4¦C, Tris-HCl buffer, pH 7.4, 40% saturated with ammonium sulfate, 6 months, kidney enzyme

Bos taurus

-

5255

4°C, in either 50 mM Tris-HCl or potassium phosphate, pH 7.4, plus 5 mM 2-mercaptoethanol, 0.02% sodium azide, 40% saturated with ammonium sulfate, 100% of initial activity for at least 6 months

Bos taurus

-

5255

4°C, in either 50 mM Tris-HCl or potassium phosphate, pH 7.4, plus 5 mM 2-mercaptoethanol, 0.02% sodium azide, no substantial loss of enzymatic activity for up to 1 month

Bos taurus

-

5255

5¦C, Tris-HCl buffer, pH 7.4, two weeks, sometimes several months

Bos taurus

-

5243