4.1.2.54: L-threo-3-deoxy-hexylosonate aldolase

This is an abbreviated version!
For detailed information about L-threo-3-deoxy-hexylosonate aldolase, go to the full flat file.

Reaction

Synonyms

GAAC, Kdg1, LGA1

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.2 Aldehyde-lyases

                4.1.2.54 L-threo-3-deoxy-hexylosonate aldolase

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Results	in table
5	AA Sequence
1	Cloned(Commentary)
1	Expression
2	General Information
1	Inhibitors
3	KM Value [mM]
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
5	Organism
5	Pathway
1	Purification (Commentary)
1	Reaction
5	Reference
1	Source Tissue
6	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 4.1.2.54 - L-threo-3-deoxy-hexylosonate aldolase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2-dehydro-3-deoxy-L-galactonate

pyruvate + L-glyceraldehyde

2 entries

pyruvate + glycolaldehyde

?

Trichoderma reesei

A6Y9S5

-

722654

-

-

?

pyruvate + L-glyceraldehyde

2-dehydro-3-deoxy-L-galactonate

Trichoderma reesei

A6Y9S5

-

722654

-

-

r

pyruvate + methylglyoxal

?

Trichoderma reesei

A6Y9S5

-

722654

-

-

?

additional information

?

-

Trichoderma reesei

A6Y9S5

the reaction with D-glyceraldehyde, dihydroxyacetone, diacetyl, acetone, glyoxal, acetaldehyde or formaldehyde plus pyruvate is below the detection limit

722654

-

-

?

2-dehydro-3-deoxy-L-galactonate

pyruvate + L-glyceraldehyde

Trichoderma reesei

A6Y9S5

the enzyme is part of the fungal pathway of D-galacturonate degradation

722654

-

-

r

2-dehydro-3-deoxy-L-galactonate

pyruvate + L-glyceraldehyde

Trichoderma reesei

A6Y9S5

the reverse reaction is significantly stronger with L-glyceraldehyde as a substrate than with D-glyceraldehyde. No activity with D-threo-3-deoxy-hexulosonate

722654

-

-

r