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4.1.2.52: 4-hydroxy-2-oxoheptanedioate aldolase

This is an abbreviated version!
For detailed information about 4-hydroxy-2-oxoheptanedioate aldolase, go to the full flat file.

Reaction

4-hydroxy-2-oxoheptanedioate
=
pyruvate
+
succinate semialdehyde

Synonyms

4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, HpaI, HpcH

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.52 4-hydroxy-2-oxoheptanedioate aldolase

Natural Substrates Products

Natural Substrates Products on EC 4.1.2.52 - 4-hydroxy-2-oxoheptanedioate aldolase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
4-hydroxy-2-oxo-heptanedioate
pyruvate + succinic semialdehyde
show the reaction diagram
-
-
-
-
?
4-hydroxy-2-oxoheptane-1,7-dioate
pyruvate + succinate semialdehyde
show the reaction diagram
-
-
-
?
4-hydroxy-2-oxoheptanedioate
pyruvate + succinate semialdehyde
show the reaction diagram
-
-
-
?
pyruvate + succinic semialdehyde
4-hydroxy-2-oxo-1,7-heptanedioate
show the reaction diagram
-
-
enzyme lacks stereospecific control producing racemic mixtures of its physiological substrate, 4-hydroxy-2-oxo-1,7-heptanedioate
-
?