4.1.2.52: 4-hydroxy-2-oxoheptanedioate aldolase

This is an abbreviated version!
For detailed information about 4-hydroxy-2-oxoheptanedioate aldolase, go to the full flat file.

Reaction

Synonyms

4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, HpaI, HpcH

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.2 Aldehyde-lyases

4.1.2.52 4-hydroxy-2-oxoheptanedioate aldolase

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Results	in table
2354	AA Sequence
3	Cloned(Commentary)
4	Crystallization (Commentary)
2	General Information
1	General Stability
7	Inhibitors
18	kcat/KM [mM/s]
8	Ki Value [mM]
24	KM Value [mM]
12	Metals/Ions
3	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
5	Organism
6	Pathway
6	PDB ID
1	pH Range
8	Protein Variants
3	Purification (Commentary)
2	Reaction
5	Reference
19	Substrates and Products (Substrate)
2	Subunits
7	Synonyms
1	Systematic Name
19	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 4.1.2.52 - 4-hydroxy-2-oxoheptanedioate aldolase

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3.55 - 941

(S)-4-hydroxy-2-oxopentanoate

2 entries

0.03868

3-deoxy-D-manno-oct-2-ulosonic acid

Escherichia coli

Q47098

i.e. KDO, pH 8.0, 25°C

721601

1000

4-hydroxy-2-oxoheptane-1,7-dioate

Escherichia coli

B1IS70

using H2O as solvent, in the presence of 0.5 mM Co2+, at pH 8.0 and 25°C

725493

1460

4-hydroxy-2-oxohexanoate

Escherichia coli

Q47098

pH 8.0, 25°C

721601

940

4-hydroxy-2-oxopentanoate

Escherichia coli

Q47098

pH 8.0, 25°C

721601

0.011 - 930

4-hydroxy-2-oxopentanoic acid

3 entries

0.4 - 3.3

acetaldehyde

2 entries

9.9

Butyraldehyde

Escherichia coli