4.1.2.52: 4-hydroxy-2-oxoheptanedioate aldolase
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For detailed information about 4-hydroxy-2-oxoheptanedioate aldolase, go to the full flat file.
Reaction
Synonyms
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, HpaI, HpcH
ECTree
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General Stability
General Stability on EC 4.1.2.52 - 4-hydroxy-2-oxoheptanedioate aldolase
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the engineering results show that His45 has a structural and catalytic role. It is important for metal cofactor binding, possibly by proper positioning of a metal cofactor water ligand and is also involved in base catalysis.