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4.1.2.50: 6-carboxytetrahydropterin synthase

This is an abbreviated version!
For detailed information about 6-carboxytetrahydropterin synthase, go to the full flat file.

Word Map on EC 4.1.2.50

Reaction

7,8-dihydroneopterin 3'-triphosphate
+
H2O
=
6-carboxy-5,6,7,8-tetrahydropterin
+
acetaldehyde
+
Triphosphate

Synonyms

6-carboxy-5,6,7,8-tetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase, CPH4 synthase, PTPS, QueD

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.50 6-carboxytetrahydropterin synthase

General Information

General Information on EC 4.1.2.50 - 6-carboxytetrahydropterin synthase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
-
QueD is one of several enzymes involved in the biosynthesis of the hypermodified nucleoside queuosine. Formation of queuosine is a multistep reaction that can be divided into three stages, overview
physiological function
-
QueD catalyzes the conversion of 7,8-dihydroneopterin triphosphate to 6-carboxy-5,6,7,8-tetrahydropterin, CPH4. QueD can also convert 6-pyruvoyltetrahydropterin, PPH4, and sepiapterin to CPH4