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4.1.2.48: low-specificity L-threonine aldolase

This is an abbreviated version!
For detailed information about low-specificity L-threonine aldolase, go to the full flat file.

Word Map on EC 4.1.2.48

Reaction

L-allo-threonine
=
glycine
+
acetaldehyde

Synonyms

GLY1, GlyA, L-TA, L-threonine aldolase, low specificity L-TA, low specificity threonine aldolase, Low-specificity L-threonine aldolase, LTA, LtaE, serine hydroxy-methyl transferase, SHMT, threonine aldolase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.48 low-specificity L-threonine aldolase

Natural Substrates Products

Natural Substrates Products on EC 4.1.2.48 - low-specificity L-threonine aldolase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
glycine + glycolaldehyde
L-4-hydroxythreonine
show the reaction diagram
-
low-specificity L-threonine aldolase is involved in a serendipitous pathway that converts 3-phosphohydroxypyruvate, an intermediate in the serine biosynthesis pathway, to L-4-phosphohydroxythreonine, an intermediate in the pyridoxal-5'-phosphate synthesis pathway in a strain of Escherichia coli that lacks 4-phosphoerythronate dehydrogenase
-
-
r
L-Thr
glycine + acetaldehyde
show the reaction diagram
additional information
?
-