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4.1.2.47: (S)-hydroxynitrile lyase

This is an abbreviated version!
For detailed information about (S)-hydroxynitrile lyase, go to the full flat file.

Word Map on EC 4.1.2.47

Reaction

an aliphatic (S)-hydroxynitrile
=
cyanide
+
an aliphatic aldehyde or ketone

Synonyms

(R)-LuHNL, (R)-Oxynitrilase, (S)-cyanohydrin producing hydroxynitrile lyase, (S)-Hb-HNL, (S)-HbHNL, (S)-HNL, (S)-Hydroxynitrile lyase, (S)-Me-HNL, (S)-MeHNL, (S)-Oxynitrilase, (S)-selective HNL, (S)-selective hydroxynitrile lyase, Acetone cyanohydrin lyase, ACL, alpha-Hydroxynitrile lyase, EC 4.1.2.37, EC 4.1.2.39, Hb-HNL, HbHNL, HNL, HNL1, Hydroxynitrile lyase, LuHNL, MeHNKL, MeHNL, mut-HNL1, Oxynitrilase, S-HnL, S-hydroxynitrile lyase, S-selective HnL, S-selective hydroxynitrile lyase, S-stereoselective HNL

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.47 (S)-hydroxynitrile lyase

Turnover Number

Turnover Number on EC 4.1.2.47 - (S)-hydroxynitrile lyase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
7.98 - 12.7
(R)-mandelonitrile
1.83 - 122
(S)-mandelonitrile
6 - 23.5
1-naphthalene carboxaldehyde
18.5
2,4-dimethylbenzaldehyde
pH 6.0, 25°C
53.6
2-Methylbenzaldehyde
pH 6.0, 25°C
0.1 - 0.6
2-nitro-1-phenylethanol
31.5 - 100
2-thiophene carboxaldehyde
28.1
3-Methoxybenzaldehyde
pH 6.0, 25°C
49.2
3-methylbenzaldehyde
pH 6.0, 25°C
9.2
4-biphenyl carboxaldehyde
pH 4.2, 22°C
26.6 - 96.6
benzaldehyde
3 - 106
mandelonitrile
91.4
piperonal
pH 6.0, 25°C
0.1 - 0.6
rac-2-nitro-1-phenylethanol
3 - 106
rac-mandelonitrile