4.1.2.44: 2,3-epoxybenzoyl-CoA dihydrolase
This is an abbreviated version!
For detailed information about 2,3-epoxybenzoyl-CoA dihydrolase, go to the full flat file.
Reaction
Synonyms
2,3-epoxybenzoyl-CoA dihydrolase, benzoyl-CoA oxidation component C, benzoyl-CoA-dihydrodiol lyase, BoxC, dihydrodiol transforming enzyme
ECTree
4.1.2.44 2,3-epoxybenzoyl-CoA dihydrolaseAdvanced search results
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Substrates Products on EC 4.1.2.44 - 2,3-epoxybenzoyl-CoA dihydrolase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O
3,4-dehydroadipyl-CoA semialdehyde + formate
the enzyme is involved in the aerobic benzoyl-CoA catabolic pathway. Benzoyl-CoA is oxidized to 2,3-dihydro-2,3-dihydroxybenzoyl-CoA (benzoyl-CoA dihydrodiol) by benzoyl-CoA oxygenase/reductase BoxBA in the presence of molecular oxygen. The next, ring cleaving step is catalysed by BoxC
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2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O
3,4-dehydroadipyl-CoA semialdehyde + formate
NADPH and semicarbazide are analysed directly by NMR spectroscopy and mass spectrometry. The purified protein does not require molecular oxygen for activity
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2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O
3,4-dehydroadipyl-CoA semialdehyde + formate
2,3-dihydro-2,3-dihydroxybenzoyl-CoA is also named 2,3-epoxybenzoyl-CoA
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2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O
3,4-dehydroadipyl-CoA semialdehyde + formate
Aromatoleum evansii KB740 (DSM Z6869)
2,3-dihydro-2,3-dihydroxybenzoyl-CoA is also named 2,3-epoxybenzoyl-CoA
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