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4.1.2.44: 2,3-epoxybenzoyl-CoA dihydrolase

This is an abbreviated version!
For detailed information about 2,3-epoxybenzoyl-CoA dihydrolase, go to the full flat file.

Reaction

2,3-epoxy-2,3-dihydrobenzoyl-CoA
+ 2 H2O =
(3Z)-6-oxohex-3-enoyl-CoA
+
formate

Synonyms

2,3-epoxybenzoyl-CoA dihydrolase, benzoyl-CoA oxidation component C, benzoyl-CoA-dihydrodiol lyase, BoxC, dihydrodiol transforming enzyme

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.44 2,3-epoxybenzoyl-CoA dihydrolase

Natural Substrates Products

Natural Substrates Products on EC 4.1.2.44 - 2,3-epoxybenzoyl-CoA dihydrolase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O
3,4-dehydroadipyl-CoA semialdehyde + formate
show the reaction diagram
the enzyme is involved in the aerobic benzoyl-CoA catabolic pathway. Benzoyl-CoA is oxidized to 2,3-dihydro-2,3-dihydroxybenzoyl-CoA (benzoyl-CoA dihydrodiol) by benzoyl-CoA oxygenase/reductase BoxBA in the presence of molecular oxygen. The next, ring cleaving step is catalysed by BoxC
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