4.1.2.32: trimethylamine-oxide aldolase
This is an abbreviated version!
For detailed information about trimethylamine-oxide aldolase, go to the full flat file.
Reaction
Synonyms
TMAO demethylase, TMAOase, Trimethylamine N-oxide aldolase, Trimethylamine N-oxide demethylase, Trimethylamine N-oxide formaldehyde-lyase, trimethylamine oxide aldolase, trimethylamine-N-oxide demethylase
ECTree
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Inhibitors
Inhibitors on EC 4.1.2.32 - trimethylamine-oxide aldolase
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ascorbate
-
activity stimulated by NADH and FMN (anaerobic) is inhibited by 40%
FeCl2
-
activity stimulated by NADH and FMN (anaerobic) is inhibited by 95% in the presence of 0.2 mM FeCl2, inhibition cannot be relieved by the presence of EDTA. Activity stimulated by ascorbate is inhibited by 94% in the presence of 0.2 mM FeCl2
iodoacetamide
-
pre-incubation results in 25% loss of activity in both cofactor systems
NaN3
-
100% inhibition of NADH/FMN cofactor system (anaerobic conditions), 40% inhibition of the ascorbate/cysteine/Fe2+ cofactor system under anaerobic conditions