4.1.2.27: sphinganine-1-phosphate aldolase

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For detailed information about sphinganine-1-phosphate aldolase, go to the full flat file.

Word Map on EC 4.1.2.27

4.1.2.27

sphingolipids

ceramide

sphingoid

egress

lymphopenia

dihydrosphingosine-1-phosphate

medicine

fingolimod

s1p-degrading

sphks

4-deoxypyridoxine

steroid-resistant

analysis

lyase-deficient

s1p-dependent

spinster

s1p-induced

Reaction

Synonyms

aldolase, dihydrosphingosine 1-phosphate, Dihydrosphingosine 1-phosphate aldolase, dihydrosphingosine phosphate lyase, Dpl1, Dpl1p, LegS2, S-1-P-lyase, S1P lyase, S1P-lyase, S1PL, S1PL2021, Sgpl1, sphinganine 1-phosphate lyase, sphinganine-1-phosphate aldolase, sphinganine-1-phosphate lyase, sphinganine-1-phosphate-alkanal-lyase, sphingosine 1-phosphate lyase, sphingosine phosphate lyase, sphingosine-1-phosphate lyase, sphingosine-phosphate lyase, SPL, SPL1

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.2 Aldehyde-lyases

4.1.2.27 sphinganine-1-phosphate aldolase

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Results	in table
114	AA Sequence
16	Application
1	CAS Registry Number
17	Cloned(Commentary)
49	Cofactor
4	Crystallization (Commentary)
466	Disease/ Diagnostics
7	Expression
42	General Information
2	General Stability
66	IC50 Value
224	Inhibitors
1	kcat/KM [mM/s]
14	Ki Value [mM]
13	KM Value [mM]
53	Localization
2	Metals/Ions
12	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
118	Organism
5	Pathway
16	PDB ID
2	pH Optimum
4	Posttranslational Modification
32	Protein Variants
6	Purification (Commentary)
18	Reaction
2	Reaction Type
115	Reference
192	Source Tissue
8	Specific Activity [micromol/min/mg]
4	Storage Stability
141	Substrates and Products (Substrate)
17	Subunits
152	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Turnover Number [1/s]

Crystallization

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Crystallization on EC 4.1.2.27 - sphinganine-1-phosphate aldolase

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hanging drop vapor diffusion method, using 20% (w/v) polypropylene glycol 400 and 10% (v/v) 1-propanol

Burkholderia pseudomallei

Q63IP8

748365

in complex with (R)-6-(4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl)nicotinonitrile, hanging drop vapor diffusion method

Homo sapiens

O95470

748366

sitting drop vapor diffusion method

2 entries