4.1.2.26: phenylserine aldolase

This is an abbreviated version!
For detailed information about phenylserine aldolase, go to the full flat file.

Reaction

Synonyms

5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase, aldolase, phenylserine

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.2 Aldehyde-lyases

4.1.2.26 phenylserine aldolase

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Results	in table
6	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
2	Cofactor
12	Inhibitors
10	kcat/KM [mM/s]
1	Ki Value [mM]
14	KM Value [mM]
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
11	Organism
1	PDB ID
3	pH Optimum
1	pH Stability
2	Protein Variants
1	Purification (Commentary)
1	Reaction
2	Reaction Type
11	Reference
21	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
18	Substrates and Products (Substrate)
4	Subunits
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
14	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 4.1.2.26 - phenylserine aldolase

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3-(ethylamino)phenol

Pseudomonas putida

Q59IT3

competitive against DL-threo-3-phenylserine

D-cycloserine

1 mM, 98% inhibition

DL-3-hydroxy-n-butyrate

Pseudomonas putida

Q59IT3

20 mM, 30% inhibition

663708

DL-3-hydroxynorvaline

Pseudomonas putida

Q59IT3

20 mM, 49% inhibition

663708

DL-3-hydroxyphenylethylamine

Pseudomonas putida

Q59IT3

20 mM, 79% inhibition

hydroxylamine

L-3-phenyllactate

10 mM, 39% inhibition

663708

p-chloromercuribenzoate

phenylhydrazine

1 mM, 52% inhibition

phosphate

Semicarbazide

1 mM, 97% inhibition