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4.1.2.20: 2-dehydro-3-deoxyglucarate aldolase

This is an abbreviated version!
For detailed information about 2-dehydro-3-deoxyglucarate aldolase, go to the full flat file.

Word Map on EC 4.1.2.20

Reaction

2-dehydro-3-deoxy-D-glucarate
=
pyruvate
 +
2-hydroxy-3-oxopropanoate

Synonyms

2-dehydro-3-deoxygalactarate aldolase, 2-keto-3-deoxy gluconate aldolase, 2-keto-3-deoxy-glucarate aldolase, 2-keto-3-deoxyglucarate aldolase, 2-keto-3-deoxygluconate-specific aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, 5-KDGluc aldolase, 5-Keto-4-deoxy-(D)-glucarate aldolase, 5-keto-4-deoxy-D-glucarate aldolase, aldolase, 2-keto-3-deoxy-D-glucarate, DDG aldolase, HpcH, KDG aldolase, KDG-specific aldolase, KDGA, KDGLucA, YagE, YfaU

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.20 2-dehydro-3-deoxyglucarate aldolase

Substrates Products

Substrates Products on EC 4.1.2.20 - 2-dehydro-3-deoxyglucarate aldolase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-dehydro-3-deoxy-6-phospho-D-gluconate
pyruvate + glyceraldehyde-3-phosphate
show the reaction diagram
-
-
-
-
?
2-dehydro-3-deoxy-D-galactonate
?
show the reaction diagram
-
-
-
?
2-dehydro-3-deoxy-D-glucarate
pyruvate + tartronate semialdehyde
show the reaction diagram
2-dehydro-3-deoxy-D-gluconate
pyruvate + glyceraldehyde
show the reaction diagram
-
the enzyme is highly specific for 2-dehydro-3-deoxy-D-gluconate with up to 2000fold higher catalytic efficiency compared to 2-dehydro-3-deoxy-6-phosphogluconate
-
-
?
2-dehydro-3-deoxy-L-rhamnonate
?
show the reaction diagram
-
-
-
?
2-keto-3-deoxy-L-lyxonate
?
show the reaction diagram
-
-
-
?
2-keto-3-deoxy-L-mannonate
?
show the reaction diagram
-
-
-
?
4-hydroxy-2-ketoheptane-1,7-dioate
pyruvate + succinic semialdehyde
show the reaction diagram
-
-
-
?
4-hydroxy-2-ketohexanoic acid
?
show the reaction diagram
-
-
-
?
4-hydroxy-2-ketopentanoic acid
?
show the reaction diagram
-
-
-
?
5-dehydro-4-deoxy-D-glucarate
pyruvate + tartronate semialdehyde
show the reaction diagram
Pyruvate + D-glyceraldehyde
?
show the reaction diagram
-
-
-
-
?
pyruvate + glyceraldehyde
?
show the reaction diagram
-
-
-
?
pyruvate + glycolaldehyde
2-oxo-4,5-dihydroxy-L-pentanoic acid
show the reaction diagram
Pyruvate + glyoxylate
?
show the reaction diagram
-
-
-
-
?
Pyruvate + L-glyceraldehyde
?
show the reaction diagram
-
-
-
-
?
pyruvate + tartronate semialdehyde
2-dehydro-3-deoxy-D-glucarate
show the reaction diagram
-
-
-
?
pyruvate + tartronate semialdehyde
5-dehydro-4-deoxy-D-glucarate
show the reaction diagram
-
-
-
?
additional information
?
-