4.1.2.14: 2-dehydro-3-deoxy-phosphogluconate aldolase

This is an abbreviated version!
For detailed information about 2-dehydro-3-deoxy-phosphogluconate aldolase, go to the full flat file.

Reaction

Synonyms

2-dehydro-3-deoxy-phosphogluconate aldolase, 2-dehydro-3-deoxyphosphogluconate aldolase, 2-keto-3-deoxy-(6-phospho)-gluconate aldolase, 2-keto-3-deoxy-6-phosphogluconate aldolase, 2-keto-3-deoxy-6-phosphogluconic aldolase, 2-keto-3-deoxygluconate-6-P-aldolase, 2-keto-3-deoxygluconate-6-phosphate aldolase, 2-oxo-3-deoxy-6-phosphogluconate aldolase, 6-phospho-2-dehydro-3-deoxy-D-gluconate D-glyceraldehyde-3-phosphate-lyase, 6-Phospho-2-keto-3-deoxygluconate aldolase, aldolase, phospho-2-keto-3-deoxygluconate, eda, KD(P)G aldolase, KDGA, KDPG aldolase, KDPG-aldolase, KDPGA, KDPGlc aldolase, ODPG aldolase, Phospho-2-dehydro-3-deoxygluconate aldolase, Phospho-2-keto-3-deoxygluconate aldolase, Phospho-2-keto-3-deoxygluconic aldolase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.2 Aldehyde-lyases

                4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase

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Results	in table
18821	AA Sequence
8	Application
1	CAS Registry Number
16	Cloned(Commentary)
1	Cofactor
16	Crystallization (Commentary)
4	General Information
2	General Stability
24	Inhibitors
14	kcat/KM [mM/s]
7	Ki Value [mM]
66	KM Value [mM]
5	Metals/Ions
20	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
113	Organism
14	Pathway
57	PDB ID
4	pH Optimum
1	pH Range
1	pH Stability
19	Protein Variants
21	Purification (Commentary)
7	Reaction
10	Reaction Type
73	Reference
12	Specific Activity [micromol/min/mg]
3	Storage Stability
161	Substrates and Products (Substrate)
17	Subunits
58	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
64	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 4.1.2.14 - 2-dehydro-3-deoxy-phosphogluconate aldolase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2,4-dinitrofluorobenzene

Pseudomonas fluorescens

-

-

4966

2,4-dioxo-4-phenylbutanoic acid

Escherichia coli

-

-

664300

2,4-dioxo-4-[2-(trifluoromethyl)phenyl]butanoic acid

Escherichia coli

-

-

664300

2,4-dioxo-4-[3-(trifluoromethyl)phenyl]butanoic acid

Escherichia coli

-

-

664300

2,4-dioxo-4-[4-(trifluoromethyl)phenyl]butanoic acid

Escherichia coli

-

-

664300

2-Keto-(3S)-3-bromopyruvate

Pseudomonas putida

-

-

4975

2-Keto-3-deoxy-6-phosphogalaconate

Pseudomonas putida

-

-

4971

2-keto-3-deoxygluconate

Pseudomonas putida

-

-

4971

4-(3-methoxyphenyl)-2,4-dioxobutanoic acid

Escherichia coli

-

-

664300

4-(4-methoxyphenyl)-2,4-dioxobutanoic acid

Escherichia coli

-

-

664300

5,5'-dithiobis(2-nitrobenzoate)

Helicobacter pylori

-

-

4983

5-Keto-4-deoxyglucarate

Pseudomonas putida

-

-

4971

acetylpyruvic acid

Escherichia coli

-

-

664300

Bromopyruvate

Pelomonas saccharophila

-

pyruvate and 2-keto-3-deoxy-6-phosphogluconate protect

4967

Cu2+

Zymomonas mobilis

-

strong

4979

iodoacetamide

Helicobacter pylori

-

-

4983

KCl

Azotobacter vinelandii

-

100 mM, 67% inhibition

4984

KI

Azotobacter vinelandii

-

100 mM, 93% inhibition

4984

NaBH4

Pseudomonas fluorescens

-

-

4965, 4966

NaBr

Azotobacter vinelandii

-

100 mM, 88% inhibition

4984

NaCl

Azotobacter vinelandii

-

100 mM, 76% inhibition

4984

NaF

Azotobacter vinelandii

-

100 mM, 45% inhibition

4984

NaI

Azotobacter vinelandii

-

100 mM, 93% inhibition

4984