4.1.2.13: fructose-bisphosphate aldolase This is an abbreviated version! For detailed information about fructose-bisphosphate aldolase, go to the full flat file .
Reaction
D-fructose 1,6-bisphosphate =
glycerone phosphate +
D-glyceraldehyde 3-phosphate
Synonyms 1,6-Diphosphofructose aldolase, 37 kDa major allergen, 41 kDa antigen, ALD, ALDC, aldoA, Aldob, aldolase, aldolase A, aldolase B, aldolase C, aldolase, fructose diphosphate, ALDP, bifunctional fructose-1,6-bisphosphate aldolase/phosphatase, Brain-type aldolase, Ca-FBA-II, CE1, CE2, class I Fba, class I fructose 1,6-bisphosphate aldolase, class I fructose bisphosphate aldolase, class I fructose-1,6-bisphosphate aldolase, class I muscle fructose bis-phosphate aldolase, class II aldolase, class II FBA, class II FBP aldolase, class II fructose 1,6-bisphosphate aldolase, class II fructose bisphosphate aldolase, class II fructose-1,6-bisphosphate aldolase, class IIa fructose 1,6-bisphosphate aldolase, class IIb fructose 1,6-bisphosphate aldolase, ClassII FBP-aldolase, CoFBA1, CoFBA2, CoFBA3, CoFBA4, D-fructose-1,6-bisphosphate aldolase, D-fructose-1,6-bisphosphate D-glyceraldehyde-3-P-lyase, D-fructose-6-phosphate aldolase, Diphosphofructose aldolase, DLF, EC 4.1.2.7, F1,6-P2 aldolase, F1,6P2 aldolase, F16BP aldolase, FBA, FBA class II, FBA-II, Fba1, Fba1p, Fba2, FBA7, FbaA, FbaB, FbaC, FBAld, FbaP, FBP aldolase, FBP aldolase/phosphatase, FBP-aldolase, FBPA, FBPA I, FBPA-1, FBPA/P, FDP aldolase, FPA, Fru-1,6-P2 aldolase, Fru-P2A, Fructoaldolase, fructose 1,6 bisphosphate aldolase, fructose 1,6-bisphosphatase/aldolase, Fructose 1,6-bisphosphate aldolase, fructose 1,6-bisphosphate aldolase/phosphatase, Fructose 1,6-diphosphate aldolase, Fructose 1-monophosphate aldolase, Fructose 1-phosphate aldolase, fructose bis-phosphate aldolase, Fructose bisphosphate aldolase, Fructose diphosphate aldolase, fructose-1,6-biphosphate aldolase, fructose-1,6-bisphosphate (FBP) aldolase/phosphatase, fructose-1,6-bisphosphate aldolase, fructose-1,6-bisphosphate aldolase A, fructose-1,6-bisphosphate aldolase B, fructose-1,6-bisphosphate aldolase class II, fructose-1,6-bisphosphate aldolase/phosphatase, fructose-1,6-bisphosphate muscle aldolase, Fructose-1,6-bisphosphate triosephosphate-lyase, fructose-bisphosphate aldolase, fructose-bisphosphate aldolase A, FSA, fuculose aldolase, heat-induced protein 44, HIP44, IgE-binding allergen, ketose 1-phosphate aldolase, Leishmania aldolase, Liver-type aldolase, MGA3_01355, MJ0400-His6, More, MtFBA, Muscle-type aldolase, Ov-fba-1, OvFBPA-1, Pcal_0111, Phosphofructoaldolase, SMALDO, SSO0286, STK_03180, TgALD1, Tneu_0133, TnFBPAP, Tt-FBPA, zerebrin II, zymohexase
ECTree
Application
Application on EC 4.1.2.13 - fructose-bisphosphate aldolase
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molecular biology
the enzyme gene controls the flux of key intermediates for oil biosynthesis
agriculture
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transgenic Nicotiana tabacum L. cv Xanthi expressing Arabidopsis plastid aldolase shows 1.4-1.9fold higher aldolase activities than wild-type, associated with enhanced growth, culminating in increased biomass, particularly under high CO2 concentration where the increase reached 2.2fold relative to wild-type plants. This increase is associated with a 1.5fold elevation of photosynthetic CO2 fixation in the transgenic plants. Overexpression results in a decrease in 3-phosphoglycerate and an increase in ribulose 1,5-bisphosphate and its immediate precursors in the Calvin cycle
agriculture
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
agriculture
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
agriculture
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
agriculture
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
agriculture
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
agriculture
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
agriculture
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
agriculture
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
agriculture
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
agriculture
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the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
diagnostics
for patients with colorectal cancer mRNA expression is a significant prognostic factor for disease-free survival and for overall survival
diagnostics
fructose-1,6-bisphosphate aldolase is an immunogenic surface target useful for the detection of Listeria genus. Listeria monocytogenes is a major public health concern and a potential economic burden regarding food industry
diagnostics
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fructose-1,6-bisphosphate aldolase is an immunogenic surface target useful for the detection of Listeria genus. Listeria monocytogenes is a major public health concern and a potential economic burden regarding food industry
-
drug development
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Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase is a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice
drug development
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
drug development
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
drug development
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
drug development
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
drug development
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
drug development
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
drug development
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
drug development
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
drug development
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
drug development
Streptococcus pneumoniae serotype 3 WU2
-
Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase is a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice
-
drug development
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future
-
food industry
fructose-1,6-bisphosphate aldolase is an immunogenic surface target useful for the detection of Listeria genus. Listeria monocytogenes is a major public health concern and a potential economic burden regarding food industry
food industry
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fructose-1,6-bisphosphate aldolase is an immunogenic surface target useful for the detection of Listeria genus. Listeria monocytogenes is a major public health concern and a potential economic burden regarding food industry
-
medicine
aldolase B deficiency causes hereditary fructose intolerance
medicine
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mutations in aldolase B gene cause hereditary fructose intolerance, most common intolerance allele encodes a A149P substitution
medicine
potential drug target
medicine
inhibitors of class II Fba can be potential drugs against microorganisms
medicine
inhibitors of class II Fba can be potential drugs against microorganisms
medicine
useful in the immunodiagnosis of malaria
medicine
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
medicine
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
medicine
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
medicine
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
medicine
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
medicine
the enzyme is a hypoxia-inducible prognostic factor for colorectal cancer
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
-
medicine
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
Listeria monocytogenes Murray B
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the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
potential drug target
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
medicine
-
the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture
-
medicine
-
the enzyme is the antigen target of the monoclonal antibody 3F8 useful for the detection of Listeria genus
-
synthesis
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enzyme FruA has a flexible substrate specificity and accepts various aldehydes. It is applcable for synthesis of a number of ketoses using simple aliphatic aldehydes as acceptors in a one-pot reaction system. The yields are quite similar for reactions of which acetaldehyde, propionaldehyde, and butyraldehyde are acceptors
synthesis
tea oil yield can be improved by enhanced expression of fructose-1,6-bisphosphate aldolase and stearoyl-ACP desaturase genes in transgenic plants