4.1.2.11: hydroxymandelonitrile lyase
This is an abbreviated version!
For detailed information about hydroxymandelonitrile lyase, go to the full flat file.
Word Map on EC 4.1.2.11
Reaction
Synonyms
(S)-HNL, (S)-Hydroxynitrile lyase, (S)-p-Hydroxy-mandelonitrile lyase, (S)-Sb-HNL, (S)-SbHNL, HNL, Hydroxynitrile lyase, Lyase, hydroxymandelonitrile, Oxynitrilase, S-Oxynitrilase, SbHNL, Sorghum hydroxynitrile lyase
ECTree
4.1.2.11 hydroxymandelonitrile lyaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 4.1.2.11 - hydroxymandelonitrile lyase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
cyanide + 4-hydroxybenzaldehyde
(S)-p-hydroxymandelonitrile
-
-
?
HCN + 3-phenylpropionaldehyde
(2S)-2-hydroxy-4-phenylbutanenitrile
-
-
17% enantiomeric excess
?
HCN + acrolein
(2S)-2-hydroxybut-3-enenitrile
-
-
25% enantiomeric excess
?
(S)-4-Hydroxymandelonitrile
Cyanide + 4-hydroxybenzaldehyde
-
-
?
(S)-4-Hydroxymandelonitrile
Cyanide + 4-hydroxybenzaldehyde
-
inactive against 2-hydroxymanelonitrile or 3-hydroxymandelonitrile
-
?
4-Hydroxymandelonitrile
?
-
involved in cyanogenesis through its ability to catalyze the stereospecific retro-addition of cyanohydrins into toxic HCN and a carbonyl compound
-
-
?
HCN + 4-hydroxybenzaldehyde
(S)-4-hydroxymandelonitrile
-
(S)-specific
-
?
HCN + 4-hydroxybenzaldehyde
(S)-4-hydroxymandelonitrile
(S)-specific
-
?
HCN + 4-hydroxybenzaldehyde
(S)-4-hydroxymandelonitrile
(S)-specific
-
?
vanillin cyanohydrin
cyanide + vanillin
-
20% the rate of 4-hydroxybenzaldehyde
-
?
additional information
?
-
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
-
?
additional information
?
-
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
?
additional information
?
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
-
?
additional information
?
-
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
-
?
additional information
?
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
?
additional information
?
-
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
?
additional information
?
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
-
?
additional information
?
-
substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates
-
?
additional information
?
-
-
When the temperature decreases from 25°C to -5°C, the enantiomeric excess increases from 18% to 30%
-
-
?
additional information
?
-
-
When the temperature decreases from 25°C to -5°C, the enantiomeric excess increases from 18% to 30%
-
?
