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4.1.1.99: phosphomevalonate decarboxylase

This is an abbreviated version!
For detailed information about phosphomevalonate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.99

Reaction

ATP
+
(R)-5-phosphomevalonate
=
ADP
+
phosphate
+
isopentenyl phosphate
+
CO2

Synonyms

HVO_1412, MvaD, PMD

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.99 phosphomevalonate decarboxylase

Inhibitors

Inhibitors on EC 4.1.1.99 - phosphomevalonate decarboxylase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
6-fluoromevalonate 5'-phosphate
negligible inhibition by 6-fluoromevalonate diphosphate (a potent inhibitor of the classical mevalonate pathway), reinforcing its selectivity for monophosphorylated ligands