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4.1.1.90: peptidyl-glutamate 4-carboxylase

This is an abbreviated version!
For detailed information about peptidyl-glutamate 4-carboxylase, go to the full flat file.

Word Map on EC 4.1.1.90

Reaction

peptidyl-4-carboxyglutamate
+
2,3-Epoxyphylloquinone
+
H2O
=
peptidyl-glutamate
+
CO2
+
O2
+
phylloquinol

Synonyms

carboxylase, Ci-GGC, gamma glutamyl carboxylase, gamma-carboxylase, gamma-glutamyl carboxylase, GGCX, glutamate carboxylase, matrix gamma-carboxyglutamate protein, matrix Gla protein, peptidyl-glutamate 4-carboxylase, peptidyl-glutamate 4-carboxylase (2-methyl-3-phytyl-1,4-naphthoquinone-epoxidizing), two-chain carboxylase, vitamin K carboxylase, vitamin K-dependent carboxylase, vitamin K-dependent gamma-glutamyl carboxylase, vitamin K-dependent gamma-glutamylcarboxylase, VKC, VKD carboxylase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.90 peptidyl-glutamate 4-carboxylase

Expression

Expression on EC 4.1.1.90 - peptidyl-glutamate 4-carboxylase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
GGCX mRNA in the urolithiasic group is lower than that in the normal control group, which is on average 7.86fold underexpressed in the urolithiasic group compared to the normal control group. Protein expression of GGCX in the urolithiasic group is weaker than that in the control groups
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