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4.1.1.88: biotin-independent malonate decarboxylase

This is an abbreviated version!
For detailed information about biotin-independent malonate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.88

Reaction

malonate
+
H+
+
Na+[side 1]
=
acetate
+
CO2
+
Na+[side 2]

Synonyms

biotin-independent malonate decarboxylase, malonate decarboxylase, malonate decarboxylase (without biotin), MdcACDE

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.88 biotin-independent malonate decarboxylase

Renatured

Renatured on EC 4.1.1.88 - biotin-independent malonate decarboxylase

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RENATURED/Commentary
ORGANISM
UNIPROT
LITERATURE
reactivation of deacetyl malonate decarboxylase with malonyl-CoA to 100%, with acetyl-CoA or methylmalonyl-CoA to about 50% of initial activity, respectively
-
reactivation of deacetyl malonate decarboxylase with malonyl-CoA, acetyl-CoA or methylmalonyl-CoA to more than 80% of initial activity
reactivation of deacetylated enzyme by incubation with acetic anhydride or malonyl-CoA
-
reacylation of the catalytically inactive SH-enzyme to form the catalytically active acetyl-S-enzyme can be achieved with acetic anhydride or more efficiently with malonyl-CoA
-