4.1.1.88: biotin-independent malonate decarboxylase

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For detailed information about biotin-independent malonate decarboxylase, go to the full flat file.

biotin-independent malonate decarboxylase, malonate decarboxylase, malonate decarboxylase (without biotin), MdcACDE

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Results	in table
4	Activating Compound
978	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
3	Cofactor
2	Crystallization (Commentary)
1	General Stability
19	Inhibitors
5	KM Value [mM]
2	Localization
20	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
13	Organism
1	pH Optimum
1	pI Value
2	Posttranslational Modification
5	Protein Variants
5	Purification (Commentary)
5	Reaction
13	Reference
5	Renatured (Commentary)
3	Specific Activity [micromol/min/mg]
2	Storage Stability
10	Substrates and Products (Substrate)
11	Subunits
4	Synonyms
1	Systematic Name

Engineering on EC 4.1.1.88 - biotin-independent malonate decarboxylase

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Q100E

the mutant of subunit MdcE has a roughly 10fold lower catalytic activity compared to the wild type enzyme

Q100E/Y102F

inactive

S142A

the mutant of subunit MdcE has a roughly 10fold lower catalytic activity compared to the wild type enzyme

Y102F

the mutant of subunit MdcE has about wild type catalytic activity

additional information