4.1.1.81: threonine-phosphate decarboxylase
This is an abbreviated version!
For detailed information about threonine-phosphate decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.81
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4.1.1.81
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enterica
-
cobalamin
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pyridoxal
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cobamides
-
aminotransferases
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histidinol
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corrin
-
decarboxylases
-
dehalogenase
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plp-dependent
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typhimurium
-
o-phosphate
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escalante-semerena
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methanosarcina
-
aldimine
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mazei
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metal-binding
- 4.1.1.81
- enterica
- cobalamin
- pyridoxal
- cobamides
- aminotransferases
- histidinol
-
corrin
- decarboxylases
-
dehalogenase
-
plp-dependent
- typhimurium
- o-phosphate
-
escalante-semerena
-
methanosarcina
-
aldimine
- mazei
-
metal-binding
Reaction
Synonyms
CobD, CobD gene product, L-Thr kinase/L-Thr-P decarboxylase, L-Thr kinase/L-Thr-phosphate decarboxylase, L-threonine-O-3-phosphate decarboxylase, MM2060, MmCobD, More, SMUL_1544
ECTree
4.1.1.81 threonine-phosphate decarboxylaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 4.1.1.81 - threonine-phosphate decarboxylase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
L-serine O-3-phosphate
ethanolamine-phosphate + CO2
-
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
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biosynthetic pathway of cobalamin, essential cofactor for many living organisms, only synthesized de novo by bacteria and archaea
precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
de novo synthesis of enzymatic cofactors, cobalamin biosynthetic pathway
precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
enzyme shows stereospecificity for the L-isomer, unable to decarboxylate the D-isomer
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
adenosylcobalamin biosynthesis, end product of the corrin ring biosynthetic pathway is 5'-deoxyadenosylcobinamide phosphate, not 5'-deoxyadenosylcobinamide
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
-
?
L-threonine O-3-phosphate
(R)-1-aminopropan-2-yl phosphate + CO2
-
-
-
-
?
additional information
?
-
bifunctional enzyme with L-threonine-O-3-phosphate decarboxylase (EC 4.1.1.81) and L-Thr kinase activities (EC 2.7.1.177). Using ATP and L-Thr as substrates, the enzyme generates ADP, L-Thr-P, and (R)-1-aminopropan-2-ol O-phosphate as products. No substrate: L-serine phosphate
-
-
?
additional information
?
-
-
bifunctional enzyme with L-threonine-O-3-phosphate decarboxylase (EC 4.1.1.81) and L-Thr kinase activities (EC 2.7.1.177). Using ATP and L-Thr as substrates, the enzyme generates ADP, L-Thr-P, and (R)-1-aminopropan-2-ol O-phosphate as products. No substrate: L-serine phosphate
-
-
?
additional information
?
-
bifunctional enzyme with L-threonine-O-3-phosphate decarboxylase (EC 4.1.1.81) and L-Thr kinase activities (EC 2.7.1.177). Using ATP and L-Thr as substrates, the enzyme generates ADP, L-Thr-P, and (R)-1-aminopropan-2-ol O-phosphate as products. No substrate: L-serine phosphate
-
-
?
additional information
?
-
-
CobD does not have lactaldehyde aminotransferase activity
-
?
additional information
?
-
CobD does not have lactaldehyde aminotransferase activity
-
?
