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4.1.1.76: arylmalonate decarboxylase

This is an abbreviated version!
For detailed information about arylmalonate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.76

Reaction

2-aryl-2-methylmalonate
=
2-arylpropanoate
 +
CO2

Synonyms

AMDase, aryl/alkenyl malonate decarboxylase, Arylmalonate decarboxylase, Arylmalonate decarboxylase (Alcaligenes bronchisepticus strain KU 1201), Decarboxylase, arylmalonate, Decarboxylase, arylmalonate (Bordetella bronchiseptica clone pAMD100 reduced), Decarboxylase, arylmalonate (Bordetella bronchiseptica strain KU1201 reduced)

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.76 arylmalonate decarboxylase

Turnover Number

Turnover Number on EC 4.1.1.76 - arylmalonate decarboxylase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
277.9
(1-benzofuran-2-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
54.8 - 147.7
(1-benzothiophen-5-yl)(hydroxy)propanedioic acid
147.7
(1-benzothiophen-6-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
23.9
(1E)-but-1-en-1-yl(methyl)propanedioic acid
wild type enzyme
12.4
(4,5-dimethylfuran-2-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
61.9
(furan-2-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
576
1-Naphthylmalonate
-
-
0.022 - 0.27
2-aryl-2-methylmalonate
23.4 - 101
2-hydroxy-2-phenylmalonic acid
55.8 - 279
2-methyl-2-phenylmalonate
1730
2-Naphthylmalonate
-
-
316 - 358
2-phenyl-2-methylmalonate
0.02 - 260
2-phenylmalonate
5320
2-Thienylmalonate
-
-
20.8 - 42.8
2-vinyl-2-methylmalonic acid
200
alpha-Methyl-alpha(2-thienyl)malonate
-
-
0.08 - 200
alpha-methyl-alpha-(alpha-thienyl)malonate
0.05 - 30.9
alpha-methyl-alpha-(beta-naphthyl)malonate
29.8
alpha-methyl-alpha-phenylmalonate
-
-
0.62 - 366
alpha-phenylmalonate
20.7
hydroxy(2-methylprop-1-en-1-yl)propanedioic acid
wild type enzyme
42.4
hydroxy(4-methylfuran-2-yl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
30.5
hydroxy(5-methoxyfuran-2-yl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
37.1
hydroxy(5-methylfuran-2-yl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
101
hydroxy(phenyl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
42.2 - 224.8
hydroxy(pyridin-3-yl)propanedioic acid
34 - 165.9
hydroxy(thiophen-2-yl)propanedioic acid
47.6
hydroxy[(1E)-prop-1-en-1-yl]propanedioic acid
wild type enzyme
1420
m-Chlorophenylmalonate
-
-
2180
m-Fluorophenylmalonate
-
-
5.2
methyl(2-methylprop-1-en-1-yl)propanedioic acid
wild type enzyme
0.12 - 31
methyl(2-naphthyl)malonic acid
0.34 - 200
methyl(2-thienyl)malonic acid
279
methyl(phenyl)propanedioic acid
wild type enzyme
46.2
methyl[(1E)-prop-1-en-1-yl]propanedioic acid
wild type enzyme
1090
o-Chlorophenylmalonate
-
-
666
o-Fluorophenylmalonate
-
-
782
p-Chlorophenylmalonate
-
-
195
p-Fluorophenylmalonate
-
-
92
p-Methoxyphenylmalonate
-
-
125
p-methylphenylmalonate
-
-
0.09 - 1143
Phenylmalonate