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4.1.1.76: arylmalonate decarboxylase

This is an abbreviated version!
For detailed information about arylmalonate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.76

Reaction

2-aryl-2-methylmalonate
=
2-arylpropanoate
+
CO2

Synonyms

AMDase, aryl/alkenyl malonate decarboxylase, Arylmalonate decarboxylase, Arylmalonate decarboxylase (Alcaligenes bronchisepticus strain KU 1201), Decarboxylase, arylmalonate, Decarboxylase, arylmalonate (Bordetella bronchiseptica clone pAMD100 reduced), Decarboxylase, arylmalonate (Bordetella bronchiseptica strain KU1201 reduced)

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.76 arylmalonate decarboxylase

Specific Activity

Specific Activity on EC 4.1.1.76 - arylmalonate decarboxylase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.05
-
mutant enzyme G74C/C188S, pH 8.5, 37°C
0.07
-
mutant enzyme S71C/C188S, pH 8.5, 37°C
0.72
-
crude cell extract
1.3
-
mutant enzyme C188S, pH 8.5, 37°C
380
-
after 528fold purification
381
-
butyl-Toyopearl, last purification step
467
-
wild type enzyme, pH 8.5, 37°C