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4.1.1.76: arylmalonate decarboxylase

This is an abbreviated version!
For detailed information about arylmalonate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.76

Reaction

2-aryl-2-methylmalonate
=
2-arylpropanoate
 +
CO2

Synonyms

AMDase, aryl/alkenyl malonate decarboxylase, Arylmalonate decarboxylase, Arylmalonate decarboxylase (Alcaligenes bronchisepticus strain KU 1201), Decarboxylase, arylmalonate, Decarboxylase, arylmalonate (Bordetella bronchiseptica clone pAMD100 reduced), Decarboxylase, arylmalonate (Bordetella bronchiseptica strain KU1201 reduced)

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.76 arylmalonate decarboxylase

KCat KM Value

KCat KM Value on EC 4.1.1.76 - arylmalonate decarboxylase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
33.9
(1-benzofuran-2-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
9.9 - 66.6
(1-benzothiophen-5-yl)(hydroxy)propanedioic acid
48.3
(1-benzothiophen-6-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
1.7
(1E)-but-1-en-1-yl(methyl)propanedioic acid
wild type enzyme
1
(4,5-dimethylfuran-2-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
6.4
(furan-2-yl)(hydroxy)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
0.0019 - 0.026
2-aryl-2-methylmalonate
3.3 - 6.6
2-hydroxy-2-phenylmalonic acid
29.53 - 36.16
2-phenyl-2-methylmalonate
0.0027 - 50
2-phenylmalonate
5.5 - 25.2
2-vinyl-2-methylmalonic acid
2.8
hydroxy(2-methylprop-1-en-1-yl)propanedioic acid
wild type enzyme
3.2
hydroxy(4-methylfuran-2-yl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
1.9
hydroxy(5-methoxyfuran-2-yl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
3.8
hydroxy(5-methylfuran-2-yl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
3.3
hydroxy(phenyl)propanedioic acid
wild type enzyme, pH and temperature not specified in the publication
3.2 - 35.3
hydroxy(pyridin-3-yl)propanedioic acid
15.2 - 38.6
hydroxy(thiophen-2-yl)propanedioic acid
5.2
hydroxy[(1E)-prop-1-en-1-yl]propanedioic acid
wild type enzyme
1.5
methyl(2-methylprop-1-en-1-yl)propanedioic acid
wild type enzyme
10.4
methyl(phenyl)propanedioic acid
wild type enzyme
3.6
methyl[(1E)-prop-1-en-1-yl]propanedioic acid
wild type enzyme
29.6 - 1499
Phenylmalonate